Metabolomics in cancer research and emerging applications in clinical oncology

DR Schmidt, R Patel, DG Kirsch… - CA: a cancer journal …, 2021 - Wiley Online Library
Cancer has myriad effects on metabolism that include both rewiring of intracellular
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …

Cancer biomarkers and their biosensors: A comprehensive review

H Khan, MR Shah, J Barek, MI Malik - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The article starts with a brief history of discovery of cancer biomarkers followed by statistical
data on published cancer biomarkers detection strategies in the last decade to demonstrate …

The dark side of lipid metabolism in prostate and renal carcinoma: novel insights into molecular diagnostic and biomarker discovery

NA di Meo, F Lasorsa, M Rutigliano… - Expert Review of …, 2023 - Taylor & Francis
Introduction Lipidomics focuses on the in-depth analysis of lipids, which are crucial
macromolecules involved in a wide range of metabolic pathways. The increased …

Biomarkers in prostate cancer diagnosis: from current knowledge to the role of metabolomics and exosomes

S Salciccia, AL Capriotti, A Laganà, S Fais… - International journal of …, 2021 - mdpi.com
Early detection of prostate cancer (PC) is largely carried out using assessment of prostate-
specific antigen (PSA) level; yet it cannot reliably discriminate between benign pathologies …

Cancer metabolomic markers in urine: evidence, techniques and recommendations

SS Dinges, A Hohm, LA Vandergrift, J Nowak… - Nature reviews …, 2019 - nature.com
Urinary tests have been used as noninvasive, cost-effective tools for screening, diagnosis
and monitoring of diseases since ancient times. As we progress through the 21st century …

The gut microbiota associated with high‐Gleason prostate cancer

M Matsushita, K Fujita, D Motooka, K Hatano… - Cancer …, 2021 - Wiley Online Library
We have found that intestinal bacteria and their metabolites, short‐chain fatty acids (SCFAs),
promote cancer growth in prostate cancer (PCa) mouse models. To clarify the association …

Advances and perspectives in prostate cancer biomarker discovery in the last 5 years through tissue and urine metabolomics

AR Lima, J Pinto, F Amaro, ML Bastos, M Carvalho… - Metabolites, 2021 - mdpi.com
Prostate cancer (PCa) is the second most diagnosed cancer in men worldwide. For its
screening, serum prostate specific antigen (PSA) test has been largely performed over the …

Metabolomics biomarkers of prostate cancer: a systematic review

M Kdadra, S Höckner, H Leung, W Kremer, E Schiffer - Diagnostics, 2019 - mdpi.com
Prostate cancer (PCa) diagnosis with current biomarkers is difficult and often results in
unnecessary invasive procedures as well as over-diagnosis and over-treatment, highlighting …

Integrative analysis of plasma metabolomics and proteomics reveals the metabolic landscape of breast cancer

R An, H Yu, Y Wang, J Lu, Y Gao, X Xie, J Zhang - Cancer & Metabolism, 2022 - Springer
Background Breast cancer (BC) is the most commonly diagnosed cancer. Currently,
mammography and breast ultrasonography are the main clinical screening methods for BC …

Urinary biomarkers and point-of-care urinalysis devices for early diagnosis and management of disease: a review

B Sequeira-Antunes, HA Ferreira - Biomedicines, 2023 - mdpi.com
Biosensing and microfluidics technologies are transforming diagnostic medicine by
accurately detecting biomolecules in biological samples. Urine is a promising biological fluid …