Metabolomics in cancer research and emerging applications in clinical oncology
Cancer has myriad effects on metabolism that include both rewiring of intracellular
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …
Cancer biomarkers and their biosensors: A comprehensive review
The article starts with a brief history of discovery of cancer biomarkers followed by statistical
data on published cancer biomarkers detection strategies in the last decade to demonstrate …
data on published cancer biomarkers detection strategies in the last decade to demonstrate …
The dark side of lipid metabolism in prostate and renal carcinoma: novel insights into molecular diagnostic and biomarker discovery
NA di Meo, F Lasorsa, M Rutigliano… - Expert Review of …, 2023 - Taylor & Francis
Introduction Lipidomics focuses on the in-depth analysis of lipids, which are crucial
macromolecules involved in a wide range of metabolic pathways. The increased …
macromolecules involved in a wide range of metabolic pathways. The increased …
Biomarkers in prostate cancer diagnosis: from current knowledge to the role of metabolomics and exosomes
Early detection of prostate cancer (PC) is largely carried out using assessment of prostate-
specific antigen (PSA) level; yet it cannot reliably discriminate between benign pathologies …
specific antigen (PSA) level; yet it cannot reliably discriminate between benign pathologies …
Cancer metabolomic markers in urine: evidence, techniques and recommendations
SS Dinges, A Hohm, LA Vandergrift, J Nowak… - Nature reviews …, 2019 - nature.com
Urinary tests have been used as noninvasive, cost-effective tools for screening, diagnosis
and monitoring of diseases since ancient times. As we progress through the 21st century …
and monitoring of diseases since ancient times. As we progress through the 21st century …
The gut microbiota associated with high‐Gleason prostate cancer
We have found that intestinal bacteria and their metabolites, short‐chain fatty acids (SCFAs),
promote cancer growth in prostate cancer (PCa) mouse models. To clarify the association …
promote cancer growth in prostate cancer (PCa) mouse models. To clarify the association …
Advances and perspectives in prostate cancer biomarker discovery in the last 5 years through tissue and urine metabolomics
AR Lima, J Pinto, F Amaro, ML Bastos, M Carvalho… - Metabolites, 2021 - mdpi.com
Prostate cancer (PCa) is the second most diagnosed cancer in men worldwide. For its
screening, serum prostate specific antigen (PSA) test has been largely performed over the …
screening, serum prostate specific antigen (PSA) test has been largely performed over the …
Metabolomics biomarkers of prostate cancer: a systematic review
M Kdadra, S Höckner, H Leung, W Kremer, E Schiffer - Diagnostics, 2019 - mdpi.com
Prostate cancer (PCa) diagnosis with current biomarkers is difficult and often results in
unnecessary invasive procedures as well as over-diagnosis and over-treatment, highlighting …
unnecessary invasive procedures as well as over-diagnosis and over-treatment, highlighting …
Integrative analysis of plasma metabolomics and proteomics reveals the metabolic landscape of breast cancer
R An, H Yu, Y Wang, J Lu, Y Gao, X Xie, J Zhang - Cancer & Metabolism, 2022 - Springer
Background Breast cancer (BC) is the most commonly diagnosed cancer. Currently,
mammography and breast ultrasonography are the main clinical screening methods for BC …
mammography and breast ultrasonography are the main clinical screening methods for BC …
Urinary biomarkers and point-of-care urinalysis devices for early diagnosis and management of disease: a review
B Sequeira-Antunes, HA Ferreira - Biomedicines, 2023 - mdpi.com
Biosensing and microfluidics technologies are transforming diagnostic medicine by
accurately detecting biomolecules in biological samples. Urine is a promising biological fluid …
accurately detecting biomolecules in biological samples. Urine is a promising biological fluid …