Stroke is the second leading cause of death worldwide and has two major subtypes:
ischemic stroke and hemorrhagic stroke. Neuroinflammation is a pathological hallmark of …

Oedema occurs when higher than normal amounts of solutes and water accumulate in
tissues. In brain parenchymal tissue, vasogenic oedema arises from changes in blood–brain …

Inflammatory responses and neuronal ferroptosis, which are associated with abnormal
accumulation of reactive oxygen species (ROS), exert crucial damaging effects on the brain …

Intracerebral hemorrhage (ICH) induces a complex sequence of apoptotic cascades and
inflammatory responses, leading to neurological impairment. Transient receptor potential …

Intracerebral hemorrhage (ICH) manifests precipitously and profoundly impairs the
neurological function in patients who are affected. The etiology of subsequent injury post …

After intracerebral hemorrhage (ICH) occurs, the overproduction of reactive oxygen species
(ROS) and iron ion overload are the leading causes of secondary damage. Removing …

Intracerebral hemorrhage (ICH) can induce intensive oxidative stress, neuroinflammation,
and brain cell apoptosis. However, conventional methods for ICH treatment have many …

Intracerebral hemorrhage (ICH), the most devastating subtype of stoke, is of high mortality at
5 years and even those survivors usually would suffer permanent disabilities. Fortunately …

Secondary brain injury exacerbates neurological dysfunction and neural cell death following
intracerebral hemorrhage (ICH), targeting the pathophysiological mechanism of the …

Background Purinergic ligand-gated ion channel 7 receptor (P2X7R) is an ATP-gated
cationic channel. It plays an important role in central nervous system diseases such as …