[PDF][PDF] Molecular diversity of the dopamine receptors

O Civelli, JR Bunzow, DK Grandy - Annual review of …, 1993 - researchgate.net
Our current understanding of the relationship between the dopaminergic system and human
brain disorders is based on two fundamental discoveries: dopamine-replacement herapy …

Dopamine functions in appetitive and defensive behaviours

JR Blackburn, JG Pfaus, AG Phillips - Progress in neurobiology, 1992 - Elsevier
1.3. The sensorimotor syndrome 2. Dopamine and feeding behaviours 2.1. Dopamine
antagonists and consummatory behaviours 2.1. 1. Initiation of consummatory behaviours …

Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals

DC MacLaren, SS Gambhir, N Satyamurthy, JR Barrio… - Gene therapy, 1999 - nature.com
Reporter genes (eg β-galactosidase, chloramphenicol-acetyltransferase, green fluorescent
protein, luciferase) play critical roles in investigating mechanisms of gene expression in …

Assays for noninvasive imaging of reporter gene expression

SS Gambhir, JR Barrio, HR Herschman… - Nuclear medicine and …, 1999 - Elsevier
Repeated, noninvasive imaging of reporter gene expression is emerging as a valuable tool
for monitoring the expression of genes in animals and humans. Monitoring of organ/cell …

Receptor-receptor interactions as an integrative mechanism in nerve cells

M Zoli, LF Agnati, PB Hedlund, XM Li, S Ferré… - Molecular …, 1993 - Springer
Several lines of evidence indicate that interactions among transmission lines can take place
at the level of the cell membrane via interactions among macromolecules, integral or …

Brain biochemistry and brain disorders

PG Strange, A Francis - Cognitive and Behavioral Neurology, 1993 - journals.lww.com
Brain Biochemistry and Brain Disorders : Cognitive and Behavioral Neurology Brain
Biochemistry and Brain Disorders : Cognitive and Behavioral Neurology Log in or Register …

New insights into dopamine receptors in the central nervous system

PG Strange - Neurochemistry international, 1993 - Elsevier
Whereas biochemical and pharmacological studies indicated that there were two
subclasses of dopamine receptor (D 1, D 2) the application of molecular biology techniques …

Pharmacological agents affecting emesis: a review (part II)

F Mitchelson - Drugs, 1992 - Springer
Part I of this article reviewed the pathophysiology of emesis, and its pharmacological
treatment. Drug-induced vomiting was also discussed. In the second part of the review, other …

Conformational Analysis of D1 Dopamine Receptor Agonists:  Pharmacophore Assessment and Receptor Mapping

DM Mottola, S Laiter, VJ Watts, A Tropsha… - Journal of medicinal …, 1996 - ACS Publications
Computer-aided conformational analysis was used to characterize the agonist
pharmacophore for D1 dopamine receptor recognition and activation. Dihydrexidine (DHX) …

Transcriptional response to cAMP in brain: specific distribution and induction of CREM antagonists

B Mellström, JR Naranjo, NS Foulkes, M Lafarga… - Neuron, 1993 - cell.com
Changes in CAMP levels are often associated with the modulation of neuronal function. The
CREM gene encodes both antagonists and activators of the CAMP-dependent …