A diverse group of toxicants has been identified that cause injury to the lung including gases
(eg, ozone, chlorine), particulates/aerosols (eg, diesel exhaust, fly ash, other combustion …

The gut microbiota is symbiotic with the human host and has been extensively studied in
recent years resulting in increasing awareness of the effects of the gut microbiota on human …

In healthy individuals, the intestinal microbiota cannot access the liver, spleen, or other
peripheral tissues. Some pathogenic bacteria can reach these sites, however, and can …

Introduction Covid-19 infection was declared a global pandemic by WHO on March 11,
2020. GRP78 protein is known to be involved in the intrusion of numerous viruses. Our …

Acute lung injury (ALI), a critical respiratory disorder that causes diffuse alveolar injury leads
to high mortality rates with no effective treatment. ALI is characterized by varying degrees of …

Patients admitted to the intensive care unit (ICU) are in need of continuous organ
replacement strategies and specialized care, for example because of neurological …

Significance: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus
causing coronavirus disease 2019 (COVID-19), affects every aspect of human life by …

Rationale: Mechanical ventilation (MV) is life-saving but may evoke ventilator-induced lung
injury (VILI). Objectives: To explore how the circadian clock modulates severity of murine …

The confluent pulmonary endothelium plays an important role as a semi-permeable barrier
between the vascular space of blood vessels and the underlying tissues, and it contributes …

Acute respiratory distress syndrome (ARDS) is characterized by increased pulmonary
inflammation and endothelial barrier permeability. Omentin has been shown to benefit …