[HTML][HTML] Diabetic retinopathy: current understanding, mechanisms, and treatment strategies
Diabetic retinopathy (DR) causes significant visual loss on a global scale. Treatments for the
vision-threatening complications of diabetic macular edema (DME) and proliferative diabetic …
vision-threatening complications of diabetic macular edema (DME) and proliferative diabetic …
Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium
JR Soucy, EA Aguzzi, J Cho, MJ Gilhooley… - Molecular …, 2023 - Springer
Retinal ganglion cell (RGC) death in glaucoma and other optic neuropathies results in
irreversible vision loss due to the mammalian central nervous system's limited regenerative …
irreversible vision loss due to the mammalian central nervous system's limited regenerative …
Pathologically high intraocular pressure disturbs normal iron homeostasis and leads to retinal ganglion cell ferroptosis in glaucoma
F Yao, J Peng, E Zhang, D Ji, Z Gao, Y Tang… - Cell Death & …, 2023 - nature.com
Glaucoma can result in retinal ganglion cell (RGC) death and permanently damaged vision.
Pathologically high intraocular pressure (ph-IOP) is the leading cause of damaged vision …
Pathologically high intraocular pressure (ph-IOP) is the leading cause of damaged vision …
Anti‐PANoptosis is involved in neuroprotective effects of melatonin in acute ocular hypertension model
D Ye, Y Xu, Y Shi, M Fan, P Lu, X Bai… - Journal of Pineal …, 2022 - Wiley Online Library
Acute ocular hypertension (AOH) is the most important characteristic of acute glaucoma,
which can lead to retinal ganglion cell (RGC) death and permanent vision loss. So far …
which can lead to retinal ganglion cell (RGC) death and permanent vision loss. So far …
[HTML][HTML] Metformin protects against retinal ischemia/reperfusion injury through AMPK-mediated mitochondrial fusion
K Zhang, T Wang, GF Sun, JX Xiao, LP Jiang… - Free Radical Biology …, 2023 - Elsevier
Retinal ischemia/reperfusion (I/R) injury is a common pathological process responsible for
cellular damage in glaucoma, diabetic retinopathy and hypertensive retinopathy. Metformin …
cellular damage in glaucoma, diabetic retinopathy and hypertensive retinopathy. Metformin …
[HTML][HTML] Osteopontin drives retinal ganglion cell resiliency in glaucomatous optic neuropathy
Chronic neurodegeneration and acute injuries lead to neuron losses via diverse processes.
We compared retinal ganglion cell (RGC) responses between chronic glaucomatous …
We compared retinal ganglion cell (RGC) responses between chronic glaucomatous …
Brimonidine is neuroprotective in animal paradigm of retinal ganglion cell damage
To investigate the neuroprotective effect of brimonidine after retinal ischemia damage on
mouse eye. Glaucoma is an optic neuropathy characterized by retinal ganglion cells (RGCs) …
mouse eye. Glaucoma is an optic neuropathy characterized by retinal ganglion cells (RGCs) …
Pyroptosis in the retinal neurovascular unit: new insights into diabetic retinopathy
C Meng, C Gu, S He, T Su, T Lhamo, D Draga… - Frontiers in …, 2021 - frontiersin.org
Diabetic retinopathy (DR) is prevalent among people with long-term diabetes mellitus (DM)
and remains the leading cause of visual impairment in working-aged people. DR is related …
and remains the leading cause of visual impairment in working-aged people. DR is related …
Delineating effects of angiopoietin-2 inhibition on vascular permeability and inflammation in models of retinal neovascularization and ischemia/reperfusion
J Canonica, R Foxton, MG Garrido, CM Lin… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Clinical trials demonstrated that co-targeting angiopoietin-2 (Ang-2) and
vascular endothelial growth factor (VEGF-A) with faricimab controls anatomic outcomes and …
vascular endothelial growth factor (VEGF-A) with faricimab controls anatomic outcomes and …
Treatment of glaucoma with natural products and their mechanism of action: An update
Glaucoma is one of the leading causes of irreversible blindness. It is generally caused by
increased intraocular pressure, which results in damage of the optic nerve and retinal …
increased intraocular pressure, which results in damage of the optic nerve and retinal …