Working toward the Future: Insights into Francisella tularensis Pathogenesis and Vaccine Development

RD Pechous, TR McCarthy… - … and molecular biology …, 2009 - Am Soc Microbiol
Francisella tularensis is a facultative intracellular gram-negative pathogen and the
etiological agent of the zoonotic disease tularemia. Recent advances in the field of …

[HTML][HTML] Rhombencephalitis Caused by Listeria monocytogenes in Humans and Ruminants: A Zoonosis on the Rise?

A Oevermann, A Zurbriggen… - … on infectious diseases, 2010 - hindawi.com
Listeriosis is an emerging zoonotic infection of humans and ruminants worldwide caused by
Listeria monocytogenes (LM). In both host species, CNS disease accounts for the high …

Mesoporous silica nanoparticles with pH-sensitive nanovalves for delivery of moxifloxacin provide improved treatment of lethal pneumonic tularemia

Z Li, DL Clemens, BY Lee, BJ Dillon, MA Horwitz… - ACS …, 2015 - ACS Publications
We have optimized mesoporous silica nanoparticles (MSNs) functionalized with pH-
sensitive nanovalves for the delivery of the broad spectrum fluoroquinolone moxifloxacin …

Innate and Adaptive Immune Responses during Listeria monocytogenes Infection

SEF D'Orazio - Microbiology Spectrum, 2019 - Am Soc Microbiol
It could be argued that we understand the immune response to infection with Listeria
monocytogenes better than the immunity elicited by any other bacteria. L. monocytogenes …

Redox‐triggered release of moxifloxacin from mesoporous silica nanoparticles functionalized with disulfide snap‐tops enhances efficacy against pneumonic tularemia …

BY Lee, Z Li, DL Clemens, BJ Dillon, AA Hwang, JI Zink… - Small, 2016 - Wiley Online Library
Effective and rapid treatment of tularemia is needed to reduce morbidity and mortality of this
potentially fatal infectious disease. The etiologic agent, Francisella tularensis, is a facultative …

[HTML][HTML] Replicating bacterium-vectored vaccine expressing SARS-CoV-2 Membrane and Nucleocapsid proteins protects against severe COVID-19-like disease in …

Q Jia, H Bielefeldt-Ohmann, RM Maison… - npj Vaccines, 2021 - nature.com
To generate an inexpensive readily manufactured COVID-19 vaccine, we employed the LVS
Δ capB vector platform, previously used to generate potent candidate vaccines against …

[HTML][HTML] COVID-19 vaccine development based on recombinant viral and bacterial vector systems: combinatorial effect of adaptive and trained immunity

MH Lee, BJ Kim - Journal of Microbiology, 2022 - Springer
Severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2) infection, which
causes coronavirus disease 2019 (COVID-19), has led to many cases and deaths …

[HTML][HTML] Live Attenuated Tularemia Vaccines for Protection Against Respiratory Challenge With Virulent F. tularensis subsp. tularensis

Q Jia, MA Horwitz - Frontiers in cellular and infection microbiology, 2018 - frontiersin.org
Francisella tularensis is the causative agent of tularemia and a Tier I bioterrorism agent. In
the 1900s, several vaccines were developed against tularemia including the killed “Foshay” …

Tularemia vaccines: recent developments and remaining hurdles

JW Conlan - Future microbiology, 2011 - Future Medicine
Francisella tularensis subsp. tularensis is a facultative intracellular bacterial pathogen of
humans and other mammals. Its inhaled infectious dose is very low and can result in very …

[HTML][HTML] Федеральные клинические рекомендации по диагностике и лечению эндокринной офтальмопатии при аутоиммунной патологии щитовидной железы

ИИ Дедов, ГА Мельниченко… - Проблемы …, 2015 - cyberleninka.ru
Эндокринная офтальмопатия (ЭОП) мультидисциплинарная проблема, находящаяся
на стыке эндокринологии и офтальмологии. Помощь больным с ЭОП недостаточна …