The host type I interferon (IFN) pathway is a major signature of inflammation induced by the
human fungal pathogen, Candida albicans. However, the molecular mechanism for …

This paper deals with specific targeting of the prodrug/enzyme regimen, CNOB/HChrR6, to
treat a serious disease, namely HER2+ human breast cancer with minimal off-target toxicity …

Extracellular vesicles (EVs) contribute to several pathophysiological processes and appear
as emerging targets for disease diagnosis and therapy. However, successful translation from …

The generation and shedding of extracellular vesicles (EVs), including exosomes and
microvesicles (MVs), by cells has emerged as a form of intercellular communication with …

Microvesicles are extracellular vesicles with diameter ranging from 100 to 1000 nm that are
secreted by tumor cells or other cells in the tumor microenvironment. A growing number of …

Cancer-derived small extracellular vesicles (sEVs) induce stromal cells to become
permissive for tumor growth. However, it is unclear whether this induction solely occurs …

Extracellular vesicles (EVs) are increasingly being recognized as candidate drug delivery
systems due to their ability to functionally transfer biological cargo between cells. However …

Extracellular vesicles (EV), including exosomes and microvesicles (MV), represent a rapidly
expanding field of research with diagnostic and therapeutic applications. Although many …

Mesenchymal stromal cells (MSCs) are attractive agents for the prophylaxis of acute graft-
versus-host disease (aGVHD) after allogeneic hematopoietic stem cell transplantation (allo …

Extracellular vesicles (EVs) are membranous containers that are secreted by multiple cell
types and actively transport biomolecules such as lipids, proteins, and nucleic acids to …