[HTML][HTML] Omics-based investigations of breast cancer
Breast cancer (BC) is characterized by an extensive genotypic and phenotypic
heterogeneity. In-depth investigations into the molecular bases of BC phenotypes …
heterogeneity. In-depth investigations into the molecular bases of BC phenotypes …
[HTML][HTML] Breast cancer: Epidemiology, risk factors and screening
H Xu, B Xu - Chinese Journal of Cancer Research, 2023 - ncbi.nlm.nih.gov
Breast cancer is a global health concern with a significant impact on the well-being of
women. Worldwide, the past several decades have witnessed changes in the incidence and …
women. Worldwide, the past several decades have witnessed changes in the incidence and …
[HTML][HTML] Prediction models for hormone receptor status in female breast cancer do not extend to males: further evidence of sex-based disparity in breast cancer
S Chatterji, JM Niehues, M van Treeck… - NPJ Breast …, 2023 - nature.com
Breast cancer prognosis and management for both men and women are reliant upon
estrogen receptor alpha (ERα) and progesterone receptor (PR) expression to inform …
estrogen receptor alpha (ERα) and progesterone receptor (PR) expression to inform …
Targeting the p53 signaling pathway in cancers: molecular mechanisms and clinical studies
J Shen, Q Wang, Y Mao, W Gao, S Duan - MedComm, 2023 - Wiley Online Library
Tumor suppressor p53 can transcriptionally activate downstream genes in response to
stress, and then regulate the cell cycle, DNA repair, metabolism, angiogenesis, apoptosis …
stress, and then regulate the cell cycle, DNA repair, metabolism, angiogenesis, apoptosis …
[HTML][HTML] Epigenetic modulation of antitumor immunity and immunotherapy response in breast cancer: biological mechanisms and clinical implications
J Yin, T Gu, N Chaudhry, NE Davidson… - Frontiers in …, 2024 - frontiersin.org
Breast cancer (BC) is the most common non-skin cancer and the second leading cause of
cancer death in American women. The initiation and progression of BC can proceed through …
cancer death in American women. The initiation and progression of BC can proceed through …
Identification of MDM2 as a prognostic and immunotherapeutic biomarker in a comprehensive pan-cancer analysis: A promising target for breast cancer, bladder …
J Zheng, F Miao, Z Wang, Y Ma, Z Lin, Y Chen, X Kong… - Life Sciences, 2023 - Elsevier
Background The murine double minute 2 (MDM2) gene is a crucial factor in the
development and progression of various cancer types. Multiple rigorous scientific studies …
development and progression of various cancer types. Multiple rigorous scientific studies …
[HTML][HTML] Biological Basis of Breast Cancer-Related Disparities in Precision Oncology Era
Precision oncology is based on deep knowledge of the molecular profile of tumors, allowing
for more accurate and personalized therapy for specific groups of patients who are different …
for more accurate and personalized therapy for specific groups of patients who are different …
[HTML][HTML] HER2-Low Expression in Male Breast Cancer: Results from a Multicenter Series in Italy
V Silvestri, V Valentini, A Bucalo, G Conti, L Manzella… - Cancers, 2024 - mdpi.com
Simple Summary In the evolving landscape of breast cancer care, recognizing HER2-low
expression as a target for anti-HER2 therapies has revolutionized treatment approaches …
expression as a target for anti-HER2 therapies has revolutionized treatment approaches …
Parthenolide-Loaded Stimuli-Responsive Cross-Linked Nanocarrier for Targeting and Killing Triple-Negative Breast Cancer Cells
S Dey, N Murmu, R Mukherjee, A Mondal… - ACS Applied Nano …, 2024 - ACS Publications
Aggressive triple-negative breast cancer (TNBC) is a current threat worldwide. The
ineffectiveness of current TNBC therapy options highlights the need for innovative …
ineffectiveness of current TNBC therapy options highlights the need for innovative …
[HTML][HTML] Exosomal microRNAs in breast cancer: towards theranostic applications
Breast cancer is one of the top two reproductive cancers responsible for high rates of
morbidity and mortality among women globally. Despite the advancements in the treatment …
morbidity and mortality among women globally. Despite the advancements in the treatment …