[HTML][HTML] Omics-based investigations of breast cancer

AN Neagu, D Whitham, P Bruno, H Morrissiey… - Molecules, 2023 - mdpi.com
Breast cancer (BC) is characterized by an extensive genotypic and phenotypic
heterogeneity. In-depth investigations into the molecular bases of BC phenotypes …

[HTML][HTML] Breast cancer: Epidemiology, risk factors and screening

H Xu, B Xu - Chinese Journal of Cancer Research, 2023 - ncbi.nlm.nih.gov
Breast cancer is a global health concern with a significant impact on the well-being of
women. Worldwide, the past several decades have witnessed changes in the incidence and …

[HTML][HTML] Prediction models for hormone receptor status in female breast cancer do not extend to males: further evidence of sex-based disparity in breast cancer

S Chatterji, JM Niehues, M van Treeck… - NPJ Breast …, 2023 - nature.com
Breast cancer prognosis and management for both men and women are reliant upon
estrogen receptor alpha (ERα) and progesterone receptor (PR) expression to inform …

Targeting the p53 signaling pathway in cancers: molecular mechanisms and clinical studies

J Shen, Q Wang, Y Mao, W Gao, S Duan - MedComm, 2023 - Wiley Online Library
Tumor suppressor p53 can transcriptionally activate downstream genes in response to
stress, and then regulate the cell cycle, DNA repair, metabolism, angiogenesis, apoptosis …

[HTML][HTML] Epigenetic modulation of antitumor immunity and immunotherapy response in breast cancer: biological mechanisms and clinical implications

J Yin, T Gu, N Chaudhry, NE Davidson… - Frontiers in …, 2024 - frontiersin.org
Breast cancer (BC) is the most common non-skin cancer and the second leading cause of
cancer death in American women. The initiation and progression of BC can proceed through …

Identification of MDM2 as a prognostic and immunotherapeutic biomarker in a comprehensive pan-cancer analysis: A promising target for breast cancer, bladder …

J Zheng, F Miao, Z Wang, Y Ma, Z Lin, Y Chen, X Kong… - Life Sciences, 2023 - Elsevier
Background The murine double minute 2 (MDM2) gene is a crucial factor in the
development and progression of various cancer types. Multiple rigorous scientific studies …

[HTML][HTML] Biological Basis of Breast Cancer-Related Disparities in Precision Oncology Era

AN Neagu, P Bruno, KR Johnson, G Ballestas… - International Journal of …, 2024 - mdpi.com
Precision oncology is based on deep knowledge of the molecular profile of tumors, allowing
for more accurate and personalized therapy for specific groups of patients who are different …

[HTML][HTML] HER2-Low Expression in Male Breast Cancer: Results from a Multicenter Series in Italy

V Silvestri, V Valentini, A Bucalo, G Conti, L Manzella… - Cancers, 2024 - mdpi.com
Simple Summary In the evolving landscape of breast cancer care, recognizing HER2-low
expression as a target for anti-HER2 therapies has revolutionized treatment approaches …

Parthenolide-Loaded Stimuli-Responsive Cross-Linked Nanocarrier for Targeting and Killing Triple-Negative Breast Cancer Cells

S Dey, N Murmu, R Mukherjee, A Mondal… - ACS Applied Nano …, 2024 - ACS Publications
Aggressive triple-negative breast cancer (TNBC) is a current threat worldwide. The
ineffectiveness of current TNBC therapy options highlights the need for innovative …

[HTML][HTML] Exosomal microRNAs in breast cancer: towards theranostic applications

R Gulati, T Mitra, R Rajiv, EJE Rajan… - Frontiers in Molecular …, 2024 - frontiersin.org
Breast cancer is one of the top two reproductive cancers responsible for high rates of
morbidity and mortality among women globally. Despite the advancements in the treatment …