Glaucoma is the result of the gradual death of retinal ganglion cells (RGCs) whose axons
form the optic nerve. Elevated intraocular pressure (IOP) is a major risk factors …

Across neurodegenerative diseases, common mechanisms may reveal novel therapeutic
targets based on neuronal protection, repair, or regeneration, independent of etiology or site …

Glaucoma is one of the world's leading causes of irreversible blindness. A complex,
multifactorial disease, the underlying pathogenesis and reasons for disease progression are …

Gene therapies, despite of being a relatively new therapeutic approach, have a potential to
become an important alternative to current treatment strategies in glaucoma. Since …

Optic neuropathies refer to a group of ocular disorders with abnormalities or dysfunction of
the optic nerve, sharing a common pathophysiology of retinal ganglion cell (RGC) death and …

Background: Glaucoma is a group of chronic diseases that cause progressive damage to the
optic nerve, resulting in irreversible and potentially debilitating visual loss. A unified …

Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible
for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent …

Eyesight is the most important of our sensory systems for optimal daily activities and overall
survival. Patients who experience visual impairment due to elevated intraocular pressure …

This study aimed to explore the role of melatonin in oxidative stress-induced injury on retinal
ganglion cells and the underlying mechanisms. The immortalized RGC-5 cells were treated …

Simple Summary Progressive loss of retinal ganglion cells in glaucoma and other optic
neuropathies results in visual deterioration and eventual blindness. Treatment options for …