COVID-19 in children: where do we stand?
GB Nikolopoulou, HC Maltezou - Archives of medical research, 2022 - Elsevier
From the beginning of the coronavirus disease 2019 (COVID-19) pandemic it became
evident that children infected with the severe acute respiratory syndrome coronavirus 2 …
evident that children infected with the severe acute respiratory syndrome coronavirus 2 …
Defining trained immunity and its role in health and disease
Immune memory is a defining feature of the acquired immune system, but activation of the
innate immune system can also result in enhanced responsiveness to subsequent triggers …
innate immune system can also result in enhanced responsiveness to subsequent triggers …
[HTML][HTML] SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition
T cell immunity is central for the control of viral infections. To characterize T cell immunity,
but also for the development of vaccines, identification of exact viral T cell epitopes is …
but also for the development of vaccines, identification of exact viral T cell epitopes is …
Trained immunity: a tool for reducing susceptibility to and the severity of SARS-CoV-2 infection
MG Netea, EJ Giamarellos-Bourboulis… - Cell, 2020 - cell.com
SARS-CoV-2 infection is mild in the majority of individuals but progresses into severe
pneumonia in a small proportion of patients. The increased susceptibility to severe disease …
pneumonia in a small proportion of patients. The increased susceptibility to severe disease …
Trained immunity: adaptation within innate immune mechanisms
J Domínguez-Andrés, JC Dos Santos… - Physiological …, 2023 - journals.physiology.org
The mechanisms underlying innate immune memory have been extensively explored in the
last decades but are in fact largely unknown. Although the specificity of adaptive immune …
last decades but are in fact largely unknown. Although the specificity of adaptive immune …
BCG vaccination in humans elicits trained immunity via the hematopoietic progenitor compartment
B Cirovic, LCJ de Bree, L Groh, BA Blok, J Chan… - Cell host & …, 2020 - cell.com
Induction of trained immunity by Bacille-Calmette-Guérin (BCG) vaccination mediates
beneficial heterologous effects, but the mechanisms underlying its persistence and …
beneficial heterologous effects, but the mechanisms underlying its persistence and …
Innate and adaptive immune memory: an evolutionary continuum in the host's response to pathogens
Immunological memory is an important evolutionary trait that improves host survival upon
reinfection. Memory is a characteristic recognized within both the innate and adaptive arms …
reinfection. Memory is a characteristic recognized within both the innate and adaptive arms …
[HTML][HTML] Innate-adaptive immunity interplay and redox regulation in immune response
Innate and adaptive immune cell activation and infiltration is the key characteristic of tissue
inflammation. The innate immune system is the front line of host defense in which innate …
inflammation. The innate immune system is the front line of host defense in which innate …
[HTML][HTML] Immune defence to invasive fungal infections: A comprehensive review
B Pathakumari, G Liang, W Liu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …
Will children reveal their secret? The coronavirus dilemma
L Cristiani, E Mancino, L Matera… - European respiratory …, 2020 - Eur Respiratory Soc
On 11 March, 2020, a novel human coronavirus, named severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) became pandemic [1]. By 24 March, 372 757 SARS-CoV-2 …
coronavirus 2 (SARS-CoV-2) became pandemic [1]. By 24 March, 372 757 SARS-CoV-2 …