Applications of single-cell sequencing in cancer research: progress and perspectives
Y Lei, R Tang, J Xu, W Wang, B Zhang, J Liu… - Journal of hematology & …, 2021 - Springer
Single-cell sequencing, including genomics, transcriptomics, epigenomics, proteomics and
metabolomics sequencing, is a powerful tool to decipher the cellular and molecular …
metabolomics sequencing, is a powerful tool to decipher the cellular and molecular …
An epigenetic role of mitochondria in cancer
Mitochondria are not only the main energy supplier but are also the cell metabolic center
regulating multiple key metaborates that play pivotal roles in epigenetics regulation. These …
regulating multiple key metaborates that play pivotal roles in epigenetics regulation. These …
Crosstalk between metabolic reprogramming and epigenetics in cancer: updates on mechanisms and therapeutic opportunities
T Ge, X Gu, R Jia, S Ge, P Chai… - Cancer …, 2022 - Wiley Online Library
Reversible, spatial, and temporal regulation of metabolic reprogramming and epigenetic
homeostasis are prominent hallmarks of carcinogenesis. Cancer cells reprogram their …
homeostasis are prominent hallmarks of carcinogenesis. Cancer cells reprogram their …
RNA methylations in human cancers
RNA methylations, as the prevalent post-transcriptional modifications, are critical in
regulating various biological processes, such as RNA transcription, splicing, structure …
regulating various biological processes, such as RNA transcription, splicing, structure …
DNA methylation in solid tumors: functions and methods of detection
A Martisova, J Holcakova, N Izadi, R Sebuyoya… - International Journal of …, 2021 - mdpi.com
DNA methylation, ie, addition of methyl group to 5′-carbon of cytosine residues in CpG
dinucleotides, is an important epigenetic modification regulating gene expression, and thus …
dinucleotides, is an important epigenetic modification regulating gene expression, and thus …
The 5-hydroxymethylcytosine landscape of prostate cancer
M Sjöström, SG Zhao, S Levy, M Zhang, Y Ning… - Cancer research, 2022 - AACR
Abstract Analysis of DNA methylation is a valuable tool to understand disease progression
and is increasingly being used to create diagnostic and prognostic clinical biomarkers …
and is increasingly being used to create diagnostic and prognostic clinical biomarkers …
Melatonin and cancer suppression: insights into its effects on DNA methylation
Melatonin is an important naturally occurring hormone in mammals. Melatonin-mediated
biological effects include the regulation of circadian rhythms, which is important for optimal …
biological effects include the regulation of circadian rhythms, which is important for optimal …
Regulation of dormancy during tumor dissemination: the role of the ECM
A Mukherjee, JJ Bravo-Cordero - Cancer and Metastasis Reviews, 2023 - Springer
The study of the metastatic cascade has revealed the complexity of the process and the
multiple cellular states that disseminated cancer cells must go through. The tumor …
multiple cellular states that disseminated cancer cells must go through. The tumor …
Estrogen receptors-mediated apoptosis in hormone-dependent cancers
A Chimento, A De Luca, P Avena, F De Amicis… - International journal of …, 2022 - mdpi.com
It is known that estrogen stimulates growth and inhibits apoptosis through estrogen receptor
(ER)-mediated mechanisms in many cancer cell types. Interestingly, there is strong evidence …
(ER)-mediated mechanisms in many cancer cell types. Interestingly, there is strong evidence …
Modification mapping by nanopore sequencing
LK White, JR Hesselberth - Frontiers in Genetics, 2022 - frontiersin.org
Next generation sequencing (NGS) has provided biologists with an unprecedented view into
biological processes and their regulation over the past 2 decades, fueling a wave of …
biological processes and their regulation over the past 2 decades, fueling a wave of …