Lipoprotein (a)[Lp (a)] has attracted the interest of researchers and physicians due to its
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …

Lipoprotein(a) Concentration and the Risk of Coronary Heart Disease, Stroke, and Nonvascular
Mortality - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

Plasma lipoprotein (a)[L p (a)] is a quantitative genetic trait with a very broad and skewed
distribution, which is largely controlled by genetic variants at the LPA locus on chromosome …

Background An increased level of Lp (a) lipoprotein has been identified as a risk factor for
coronary artery disease that is highly heritable. The genetic determinants of the Lp (a) …

Human epidemiologic and genetic evidence using the Mendelian randomization approach
in large-scale studies now strongly supports that elevated lipoprotein (a)[Lp (a)] is a causal …

Background: Lipoprotein-related traits have been consistently identified as risk factors for
atherosclerotic cardiovascular disease, largely on the basis of studies of coronary artery …

Background: Coronary heart disease (CHD) is a leading cause of death globally. Although
therapy with statins decreases circulating levels of low-density lipoprotein cholesterol and …

Apolipoprotein (a)(apo (a)) is the protein component that defines lipoprotein (a)(Lp (a))
particles and is encoded by the LPA gene. The apo (a) is extremely heterogeneous in size …

Background Current data from individual studies present conflicting evidence about the
relationship between risk factors and cardiovascular disease (CVD) in heterozygous familial …

Objective—Increased levels of lipoprotein (a) are a highly heritable risk factor for coronary
artery disease (CAD). The genetic determinants of lipoprotein (a) levels are mainly because …