Background. Opioids are the cornerstone of the therapy used in both acute and chronic pain
syndromes to treat pain of moderate to severe intensity. The knowledge that opioid receptors …

US8499966B2 - Method of moving a delivery member of a dispensing device for
administration of oral transmucosal dosage forms - Google Patents US8499966B2 - Method of …

Objective A major goal of palliative care is to provide comfort, and pain is one of the most
common causes of treatable suffering in patients with advanced disease. Opioids are …

Drug storage and dispensing devices for dispensing a drug dosage form are disclosed.
Devices having a housing defining a nonlinear passageway and a flexible push rod to move …

Methadone has several unique characteristics that make it an attractive option for pain relief
in serious illness, but the safety of methadone has been called into question after reports of …

Context Perinatal palliative care is an area of increasing focus among clinicians supporting
newborns and their families. Although not every newborn will survive the neonatal period …

Abstract Systems and methods for administration of small volume sufentanil drug dosage
forms to the sublingual mucosa of a subject using a device are disclosed. The dispensing …

5,263,596 A* 1 1/1993 Williams...................... 221 153 2003/0052787 A1 3/2003 Zerhusen et
al. 5,292,307 A 3, 1994 Dolzine et al. 2003/OO77300 A1 4/2003 Wermeling et al. 5,296,234 …

Drug release within the oral cavity can be of paramount importance for formulations that are
designed for specific purposes such as taste-masking, faster onset of therapeutic action …

Pain is an unfortunate constant in the lives of most patients with epidermolysis bullosa (EB),
1 especially for those with the more severe types of EB. In a survey of 140 patients with all …