Comprehensive review of uterine fibroids: developmental origin, pathogenesis, and treatment
Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …
Short chain fatty acid metabolism in relation to gut microbiota and genetic variability
It is widely accepted that the gut microbiota plays a significant role in modulating
inflammatory and immune responses of their host. In recent years, the host-microbiota …
inflammatory and immune responses of their host. In recent years, the host-microbiota …
Assessment of corneal substrate biomechanics and its effect on epithelial stem cell maintenance and differentiation
Whilst demonstrated extensively in vitro, the control of cell behaviour via modulation of
substrate compliance in live tissues has not been accomplished to date. Here we propose …
substrate compliance in live tissues has not been accomplished to date. Here we propose …
[HTML][HTML] Therapeutic applications of collagenase (metalloproteases): A review
H Alipour, A Raz, S Zakeri, ND Djadid - Asian Pacific Journal of Tropical …, 2016 - Elsevier
Non-invasive therapeutic methods have recently been used in medical sciences. Enzymes
have shown high activity at very low concentrations in laboratories and pharmaceutical …
have shown high activity at very low concentrations in laboratories and pharmaceutical …
Dynamic reciprocity between cells and their microenvironment in reproduction
JT Thorne, TR Segal, S Chang, S Jorge… - Biology of …, 2015 - academic.oup.com
Dynamic reciprocity (DR) refers to the ongoing, bidirectional interaction between cells and
their microenvironment, specifically the extracellular matrix (ECM). The continuous …
their microenvironment, specifically the extracellular matrix (ECM). The continuous …
Extracellular matrix and Hippo signaling as therapeutic targets of antifibrotic compounds for uterine fibroids
Background Uterine fibroids are highly prevalent, collagen‐rich, mechanically stiff, fibrotic
tumors for which new therapeutic options are needed. Increased extracellular matrix (ECM) …
tumors for which new therapeutic options are needed. Increased extracellular matrix (ECM) …
Evidence of biomechanical and collagen heterogeneity in uterine fibroids
FL Jayes, B Liu, L Feng, N Aviles-Espinoza, S Leikin… - PLoS …, 2019 - journals.plos.org
Objective Uterine fibroids (leiomyomas) are common benign tumors of the myometrium but
their molecular pathobiology remains elusive. These stiff and often large tumors contain …
their molecular pathobiology remains elusive. These stiff and often large tumors contain …
The evolving role of natural compounds in the medical treatment of uterine fibroids
M Ciebiera, M Ali, L Prince, T Jackson-Bey… - Journal of clinical …, 2020 - mdpi.com
Uterine fibroids (UFs) remain a significant health issue for many women, with a
disproportionate impact on women of color, likely due to both genetic and environmental …
disproportionate impact on women of color, likely due to both genetic and environmental …
Evidence-based approach for secondary prevention of uterine fibroids (The ESCAPE approach)
Uterine fibroids (UFs) are common tumors in women of reproductive age. It is imperative to
comprehend UFs' associated risk factors to facilitate early detection and prevention. Simple …
comprehend UFs' associated risk factors to facilitate early detection and prevention. Simple …
[HTML][HTML] Prevention of uterine fibroids: Molecular mechanisms and potential clinical application
Uterine fibroids (UFs; leiomyoma) are the most common benign neoplastic threat to women
worldwide, exacting an immense personal burden on female health and a monetary …
worldwide, exacting an immense personal burden on female health and a monetary …