A hallmark of cancer is the ability of tumor cells to avoid immune destruction. Activated
immune cells in tumor microenvironment (TME) secrete proinflammatory cytokines and …

The variety of diseases caused by mutations in RET receptor tyrosine kinase provides a
classic example of phenotypic heterogeneity. Gain-of-function mutations of RET are …

Distinguishing follicular variant of papillary carcinoma (FVPC) from follicular adenoma and
follicular carcinoma can be difficult if nuclear features of papillary carcinoma are not well …

The RET gene encodes a receptor tyrosine kinase that is expressed in neural crest-derived
cell lineages. The RET receptor plays a crucial role in regulating cell proliferation, migration …

Some cancer types are strongly associated with chronic inflammatory or infectious diseases
whereas others are not, but an inflammatory component is present in most human neoplastic …

In different human carcinoma types, mast cell infiltrate increases with respect to normal
tissue and mast cell density correlates with a bad prognosis. To assess the role of mast cells …

Objective To investigate the association between juvenile autoimmune thyroiditis (JAT) and
thyroid cancer in pediatric patients. Design We conducted a retrospective study among …

Aims Conflicting data have been reported with regard to Hashimoto thyroiditis (HT) and risk
of malignancy. The aim of this study was to evaluate coexistence of papillary thyroid cancer …

Background Between 10 and 30% of the fine needle aspiration biopsies (FNABs) of thyroid
nodules are diagnosed as 'indeterminate'. A molecular diagnostic method is needed to …

Background: This study examined the risk of cancer in patients with Hashimoto's thyroiditis
(HT). Methods: The Taiwanese National Health Insurance Research Database (NHIRD) was …