Eosinophil responses during COVID-19 infections and coronavirus vaccination

AW Lindsley, JT Schwartz, ME Rothenberg - Journal of Allergy and Clinical …, 2020 - Elsevier
Eosinophils are circulating and tissue-resident leukocytes that have potent proinflammatory
effects in a number of diseases. Recently, eosinophils have been shown to have various …

[HTML][HTML] The biology of eosinophils and their role in asthma

CN McBrien, A Menzies-Gow - Frontiers in medicine, 2017 - frontiersin.org
This review will describe the structure and function of the eosinophil. The roles of several
relevant cell surface molecules and receptors will be discussed. We will also explore the …

The role of peripheral blood eosinophil counts in COVID‐19 patients

G Xie, F Ding, L Han, D Yin, H Lu, M Zhang - Allergy, 2021 - Wiley Online Library
Abstract Background Coronavirus disease 2019 (COVID‐19) emerged in Wuhan city and
rapidly spread globally outside China. We aimed to investigate the role of peripheral blood …

[HTML][HTML] Human antimicrobial peptides as therapeutics for viral infections

A Ahmed, G Siman-Tov, G Hall, N Bhalla, A Narayanan - Viruses, 2019 - mdpi.com
Successful in vivo infection following pathogen entry requires the evasion and subversion of
multiple immunological barriers. Antimicrobial peptides (AMPs) are one of the first immune …

[HTML][HTML] Eosinophil granule proteins: form and function

KR Acharya, SJ Ackerman - Journal of Biological Chemistry, 2014 - ASBMB
Experimental and clinical data strongly support a role for the eosinophil in the pathogenesis
of asthma, allergic and parasitic diseases, and hypereosinophilic syndromes, in addition to …

The eosinophil

ME Rothenberg, SP Hogan - Annu. Rev. Immunol., 2006 - annualreviews.org
Eosinophils have been considered end-stage cells involved in host protection against
parasites. However, numerous lines of evidence have now changed this perspective by …

[HTML][HTML] Key mechanisms governing resolution of lung inflammation

CT Robb, KH Regan, DA Dorward, AG Rossi - Seminars in …, 2016 - Springer
Innate immunity normally provides excellent defence against invading microorganisms.
Acute inflammation is a form of innate immune defence and represents one of the primary …

[HTML][HTML] mRNA is an endogenous ligand for Toll-like receptor 3

K Karikó, H Ni, J Capodici, M Lamphier… - Journal of Biological …, 2004 - ASBMB
Toll-like receptors (TLRs) are the basic signaling receptors of the innate immune system.
They are activated by molecules associated with pathogens or injured host cells and tissue …

Eosinophils: biological properties and role in health and disease

SP Hogan, HF Rosenberg, R Moqbel… - Clinical & …, 2008 - Wiley Online Library
Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation
of diverse inflammatory responses, as well as modulators of innate and adaptive immunity …

Angiogenins: a new class of microbicidal proteins involved in innate immunity

LV Hooper, TS Stappenbeck, CV Hong, JI Gordon - Nature immunology, 2003 - nature.com
Although angiogenins have been implicated in tumor-associated angiogenesis, their normal
physiologic function remains unclear. We show that a previously uncharacterized …