Application of Growth Hormone in in vitro Fertilization

YM Xu, GM Hao, BL Gao - Frontiers in endocrinology, 2019 - frontiersin.org
Growth hormone (GH) is a peptide hormone secreted mainly by the anterior part of the
pituitary gland and plays a critical role in cell growth, development, and metabolism …

The evolving concept of poor-prognosis for women undertaking IVF and the notion of growth hormone as an adjuvant; a single-center viewpoint

JL Yovich, Y Ye, SLP Regan, KN Keane - Frontiers in Endocrinology, 2019 - frontiersin.org
IVF is currently regarded as a successful new technology with the number of IVF children
currently well over 8 million worldwide. This has been achieved by an explosive plethora of …

The addition of growth hormone adjuvant therapy to the long down regulation protocol in poor responders undergoing in vitro fertilization: randomized control trial

DMR Dakhly, YA Bassiouny, YA Bayoumi… - European Journal of …, 2018 - Elsevier
Objective to detect the impact of growth hormone (GH) co-treatment to the long down
regulation protocol, on the outcomes of IVF/ICSI cycles in poor responders. Study Design …

Follicular fluid growth factors and interleukin profiling as potential predictors of IVF outcomes

B Molka, B Gwladys, B Dorian, M Lucie… - Frontiers in …, 2022 - frontiersin.org
Growth hormone (GH) has gained attention as an anti-aging compound enhancing oocyte
quality. In fact, GH is known to activate intrafollicular metabolic events for oocyte maturation …

Low dose growth hormone adjuvant treatment with ultra-long ovarian stimulation protocol in poor responders showed non-inferior pregnancy outcome compared with …

YX Lee, MS Shen, CR Tzeng - Frontiers in Endocrinology, 2019 - frontiersin.org
Background: Growth hormone (GH) has long been used as adjuvant treatment in ovarian
stimulation for in vitro fertilization (IVF), especially in poor responder (PR) patients. However …

Comparative efficacy of different growth hormone supplementation protocols in improving clinical outcomes in women with poor ovarian response undergoing …

Z Xu, W Tong, Z Yang, H Zhang, X Chen - Scientific Reports, 2024 - nature.com
Growth hormone (GH) has a long-standing history of use as an adjunctive therapy in the
treatment of poor ovarian response (POR), but the optimal dosage and timing remains …

[HTML][HTML] Live birth outcomes of vitrified embryos generated under growth hormone stimulation are improved for women categorized as poor-prognosis

KN Keane, Y Ye, PM Hinchliffe… - Clinical and …, 2019 - ncbi.nlm.nih.gov
Objective To determine the clinical pregnancy (CP) and live birth (LB) rates arising from
frozen embryo transfers (FETs) that had been generated under the influence of in vitro …

Impact of Follicle Stimulating Hormone Receptor (FSHR) Polymorphism on the Efficiency of Co-Treatment with Growth Hormone in a Group of Infertile Women from …

M Surcel, B Doroftei, IA Neamtiu, D Muresan… - Diagnostics, 2022 - mdpi.com
“Poor responders”(PR) are an important category of infertile women who experience a
modest response to controlled ovarian stimulation. In this study, we evaluated response to …

Human growth hormone use in poor ovarian response–caution and opportunities

RJ Norman, RJ Hart - Therapeutic advances in reproductive …, 2021 - journals.sagepub.com
Human growth hormone has found favour as a co-gonadotrophin in assisted reproduction
particularly in the circumstances of a poor response to stimulation. Its use has been based …

Effect of growth hormone cotreatment in sub-fertile women≥ 40 years: a meta-analysis

M Elkalyoubi, L Schindler… - Reproduction and Fertility, 2023 - raf.bioscientifica.com
Treatment of sub-fertile women aged≥ 40 years old (advanced maternal age (AMA)) is
challenging. Co-treatment with growth hormone (GH) is suggested to improve reproductive …