Managing hyperlipidaemia in patients with COVID-19 and during its pandemic: An expert panel position statement from HEART UK
The emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) which causes Coronavirus Disease 2019 (COVID-19) has resulted in a pandemic. SARS …
2) which causes Coronavirus Disease 2019 (COVID-19) has resulted in a pandemic. SARS …
Molecular targets of statins and their potential side effects: Not all the glitter is gold
KK Patel, VS Sehgal, K Kashfi - European journal of pharmacology, 2022 - Elsevier
Statins are a class of drugs widely used worldwide to manage hypercholesterolemia and the
prevention of secondary heart attacks. Currently, available statins vary in terms of their …
prevention of secondary heart attacks. Currently, available statins vary in terms of their …
Flavonoid-statin interactions causing myopathy and the possible significance of OATP transport, CYP450 metabolism and mevalonate synthesis
J Zechner, SM Britza, R Farrington, RW Byard… - Life Sciences, 2022 - Elsevier
hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitors, statins, are a
primary treatment for hyperlipidemic cardiovascular diseases which are a leading global …
primary treatment for hyperlipidemic cardiovascular diseases which are a leading global …
Detection of statin-induced rhabdomyolysis and muscular related adverse events through data mining technique
P Kunakorntham, O Pattanaprateep… - BMC Medical Informatics …, 2022 - Springer
Background and objective Rhabdomyolysis (RM) is a life-threatening adverse drug reaction
in which statins are the one commonly related to RM. The study aimed to explore the …
in which statins are the one commonly related to RM. The study aimed to explore the …
Bile acid/fatty acid integrated nanoemulsomes for nonalcoholic fatty liver targeted lovastatin delivery; stability, in-vitro, ex-vivo, and in-vivo analyses
Background Controlled and targeted drug delivery to treat nonalcoholic fatty liver disease
(NAFLD) can benefit from additive attributes of natural formulation ingredients incorporated …
(NAFLD) can benefit from additive attributes of natural formulation ingredients incorporated …
Safety and tolerability of antimicrobial agents in the older patient
L Soraci, A Cherubini, L Paoletti, G Filippelli, F Luciani… - Drugs & Aging, 2023 - Springer
Older patients are at high risk of infections, which often present atypically and are associated
with high morbidity and mortality. Antimicrobial treatment in older individuals with infectious …
with high morbidity and mortality. Antimicrobial treatment in older individuals with infectious …
Influence of Tyrosine Kinase Inhibition on Organic Anion Transporting Polypeptide 1B3-Mediated Uptake
VN Hove, K Anderson, ER Hayden… - Molecular …, 2022 - ASPET
The organic anion transporting polypeptide family member (OATP) 1B3 is a hepatic uptake
transporter that has a broad substrate recognition and plays a significant role in regulating …
transporter that has a broad substrate recognition and plays a significant role in regulating …
Colchicine use and risks of stroke recurrence in acute non-cardiogenic ischemic stroke patients: a population-based cohort study
Background: The objective is to study whether the cardiovascular protective effects of
colchicines could be applied to non-cardiogenic ischemic stroke (IS) patients. Patients and …
colchicines could be applied to non-cardiogenic ischemic stroke (IS) patients. Patients and …
Antibiotics and Lipid-Modifying Agents: Potential Drug–Drug Interactions and Their Clinical Implications
M Spanakis, D Alon-Ellenbogen, P Ioannou… - Pharmacy, 2023 - mdpi.com
Evidence-based prescribing requires taking into consideration the many aspects of optimal
drug administration (eg, dosage, comorbidities, co-administered drugs, etc.). A key issue is …
drug administration (eg, dosage, comorbidities, co-administered drugs, etc.). A key issue is …
Integrative proteomics and metabolomics approach to elucidate the antimicrobial effect of simvastatin on Escherichia coli
Globally, simvastatin is one of the most commonly used statin drugs. Its antimicrobial
properties have been investigated against various pathogens. However, its effect on …
properties have been investigated against various pathogens. However, its effect on …