An important goal of biomedical research is to translate basic research findings into useful
medical advances. In the field of neuropharmacology this requires understanding disease …

After nearly half a century on the market, ketamine still occupies a unique corner in the
medical armamentarium of anesthesiologists or clinicians treating pain. Over the last two …

In the biomedical area, the interdisciplinary field of nanotechnology has the potential to bring
numerous unique applications, including better tactics for cancer detection, diagnosis, and …

Gastrointestinal (GI) pain—a form of visceral pain—is common in some disorders, such as
irritable bowel syndrome, Crohn's disease and pancreatitis. However, identifying the cause …

Background: Pain of a moderate or severe intensity affects over half of patients with
advanced cancer and remains undertreated in at least one-third of these patients. Aim: The …

The efficacy of pregabalin in acute postsurgical pain has been demonstrated in numerous
studies; however, the analgesic efficacy and adverse effects of using pregabalin in various …

Paracetamol (acetaminophen)(PAR), caffeine (CAF) and tramadol hydrochloride (TRA) are
important drugs widely used for many clinical purposes. Determination of their contents is of …

Chronic neuropathic pain is a debilitating ordeal for patients worldwide and
pharmacological treatment efficacy is still limited. As many pharmacological interventions for …

Pain is one of the most challenging symptoms for patients with rheumatoid arthritis (RA). RA-
related pain is frequently considered to be solely a consequence of inflammation in the …

In last decades, knowledge of nociceptive pain mechanisms has expanded rapidly. The use
of quantitative sensory testing has provided evidence that peripheral and central …