Progress in Topical and Transdermal Drug Delivery Research—Focus on Nanoformulations

D Lunter, V Klang, A Eichner, SM Savic, S Savic… - Pharmaceutics, 2024 - mdpi.com
Skin is the largest organ and a multifunctional interface between the body and its
environment. It acts as a barrier against cold, heat, injuries, infections, chemicals, radiations …

Graphene Oxide (GO) for the Treatment of Bone Cancer: A Systematic Review and Bibliometric Analysis

LV Barba-Rosado, DC Carrascal-Hernández… - Nanomaterials, 2024 - mdpi.com
Cancer is a severe disease that, in 2022, caused more than 9.89 million deaths worldwide.
One worrisome type of cancer is bone cancer, such as osteosarcoma and Ewing tumors …

Multifunctional Inorganic–Organic Composite Carriers for Synergistic Dual Therapy of Melanoma

KA Mitusova, DR Akhmetova, A Rogova… - ACS Biomaterials …, 2024 - ACS Publications
Many methods for cancer treatment have been developed. Among them photothermal
therapy (PTT) has drawn the most significant attention due to its noninvasiveness, remote …

Cubosomes and hexosomes stabilized by sorbitan monooleate as biocompatible nanoplatforms against skin metastatic human melanoma

M Fornasier, K Krautforst, J Kulbacka, P Jönsson… - Journal of Colloid and …, 2024 - Elsevier
Nanoparticles have become versatile assets in the medical field, providing notable benefits
across diverse medical arenas including controlled drug delivery, imaging, and …

Indocyanine green-loaded N-doped carbon quantum dot nanoparticles for effective photodynamic therapy and cell imaging of melanoma cancer: In vitro, ex vivo and …

H Mehravanfar, N Farhadian… - Journal of Drug Targeting, 2024 - Taylor & Francis
N-doped carbon quantum dot (CQD) nanoparticle was prepared as a novel nanocarrier with
excellent solubility, stability, and high quantum yield to overcome Indocyanine Green (ICG) …

Evaluation of polyelectrolyte nanoparticles of chitosan and hyaluronic acid as topical delivery systems for cytotoxic agents

CM Hirokawa, JS Passos, JR Nunes… - Colloids and Surfaces A …, 2024 - Elsevier
In this study, we developed polyelectrolyte complexes (PECs), composed of hyaluronic acid
and chitosan, aiming at obtaining a bioadhesive topical formulation for potential application …

Combining photodynamic therapy and cascade chemotherapy for enhanced tumor cytotoxicity: the role of CTT2P@B nanoparticles

R Wang, H Li, L Han, B Han, Y Bao, H Fan… - … in Bioengineering and …, 2024 - frontiersin.org
The mitochondria act as the main producers of reactive oxygen species (ROS) within cells.
Elevated levels of ROS can activate the mitochondrial apoptotic pathway, leading to cell …

Microneedle system for tissue engineering and regenerative medicines: a smart and efficient therapeutic approach

MUA Khan, MA Aslam, MFB Abdullah, H Gul… - …, 2024 - iopscience.iop.org
The global demand for an enhanced quality of life and extended lifespan has driven
significant advancements in tissue engineering and regenerative medicine. These fields …

Nano-mediated strategy: recent advance in the application of drug delivery systems in melanoma treatment and diagnosis

Y Wang, Y Tian, L Jia, S Xu, X Meng - Biomedical Materials, 2024 - iopscience.iop.org
Melanoma is a common malignant tumor, with a five-year mortality rate as high as 62% in
cases of metastatic melanoma according to cancer statistics (2024). In recent years, the …

Advancing therapeutic efficacy: nanovesicular delivery systems for medicinal plant-based therapeutics

MJ Saadh, MA Mustafa, S Kumar, P Gupta… - Naunyn-Schmiedeberg's …, 2024 - Springer
The utilization of medicinal plant extracts in therapeutics has been hindered by various
challenges, including poor bioavailability and stability issues. Nanovesicular delivery …