[HTML][HTML] Phase II study of novel orally PI3Kα/δ inhibitor TQ-B3525 in relapsed and/or refractory follicular lymphoma
H Wang, J Feng, Y Liu, Z Qian, D Gao, X Ran… - … and Targeted Therapy, 2024 - nature.com
This registration study assessed clinical outcomes of TQ-B3525, the dual
phosphatidylinositol-3-kinase (PI3K) α/δ inhibitor, in relapsed and/or refractory follicular …
phosphatidylinositol-3-kinase (PI3K) α/δ inhibitor, in relapsed and/or refractory follicular …
Synthesis and application of small molecules approved for the treatment of lymphoma
YY Guo, JY Zhang, JF Sun, P Nie, H Gao - European Journal of Medicinal …, 2023 - Elsevier
Lymphoma is a form of cancer that impacts the lymphatic system, which plays a crucial role
in defending the body against infections and illnesses. It is characterized by the atypical …
in defending the body against infections and illnesses. It is characterized by the atypical …
[HTML][HTML] Targeted Therapy in Follicular Lymphoma: Towards a Chemotherapy-Free Approach
CJJ Chen, MY Choi, BM Heyman - Cancers, 2023 - mdpi.com
Simple Summary Follicular lymphoma (FL)—a common, indolent, and usually non-curable B-
cell non-Hodgkin lymphoma—is frequently treated with cytotoxic chemotherapy with anti …
cell non-Hodgkin lymphoma—is frequently treated with cytotoxic chemotherapy with anti …
Integrative genomic and transcriptomic analysis reveals genetic alterations associated with the early progression of follicular lymphoma
F Gao, H Liu, X Meng, J Liu, J Wang… - British Journal of …, 2023 - Wiley Online Library
Follicular lymphoma (FL), the most common indolent lymphoma, is a clinically and
genetically heterogeneous disease. However, the prognostic value of driver gene mutations …
genetically heterogeneous disease. However, the prognostic value of driver gene mutations …
[HTML][HTML] Patient-derived follicular lymphoma spheroids recapitulate lymph node signaling and immune profile uncovering galectin-9 as a novel immunotherapeutic …
C Dobaño-López, JG Valero, F Araujo-Ayala… - Blood Cancer …, 2024 - nature.com
Follicular lymphoma (FL), the most common indolent non-Hodgkin lymphoma, constitutes a
paradigm of immune tumor microenvironment (TME) contribution to disease onset …
paradigm of immune tumor microenvironment (TME) contribution to disease onset …
Alterations in Genome Organization in Lymphoma Cell Nuclei due to the Presence of the t (14; 18) Translocation
E Garimberti, C Federico, D Ragusa, F Bruno… - International Journal of …, 2024 - mdpi.com
Chromosomal rearrangements have been shown to alter genome organization,
consequently having an impact on gene expression. Studies on certain types of leukemia …
consequently having an impact on gene expression. Studies on certain types of leukemia …
[HTML][HTML] Case Report: CD19 CAR T-cell therapy following autologous stem cell transplantation: a successful treatment for R/R CD20-negative transformed follicular …
J Zhang, D Cai, R Gao, Y Miao, Y Cui, Z Liu… - Frontiers in …, 2023 - frontiersin.org
Background Follicular lymphoma (FL), a common indolent B-cell lymphoma, has the
potential to transform into an aggressive lymphoma, such as diffuse large B-cell lymphoma …
potential to transform into an aggressive lymphoma, such as diffuse large B-cell lymphoma …
[HTML][HTML] CT Images in Follicular Lymphoma: Changes after Treatment Are Predictive of Cardiac Toxicity in Patients Treated with Anthracycline-Based or RB Regimens
F Esposito, V Mezzanotte, C Tesei, A Luciano… - Cancers, 2024 - mdpi.com
Simple Summary Epicardial adipose tissue radio intensity and myocardial extracellular
volume in computed tomography were investigated and evaluated at disease onset and …
volume in computed tomography were investigated and evaluated at disease onset and …
Characterization of Human B Cell Hematological Malignancies Using Protein-Based Approaches
C Jiménez, A Garrote-de-Barros… - International Journal of …, 2024 - mdpi.com
The maturation of B cells is a complex, multi-step process. During B cell differentiation,
errors can occur, leading to the emergence of aberrant versions of B cells that, finally …
errors can occur, leading to the emergence of aberrant versions of B cells that, finally …
[HTML][HTML] Raptor mediates the selective inhibitory effect of cardamonin on RRAGC-mutant B cell lymphoma
Y Liu, Y Zhu, H Chen, J Zhou, P Niu, D Shi - … Complementary Medicine and …, 2023 - Springer
Background mTORC1 (mechanistic target of rapamycin complex 1) is associated with
lymphoma progression. Oncogenic RRAGC (Rag guanosine triphosphatase C) mutations …
lymphoma progression. Oncogenic RRAGC (Rag guanosine triphosphatase C) mutations …