Antimicrobial activity of natural and semi-synthetic carbazole alkaloids

YY Ding, H Zhou, BQ Zhang, ZJ Zhang… - European Journal of …, 2023 - Elsevier
Since the first natural carbazole alkaloid, murrayanine, was isolated from Mwraya Spreng,
carbazole alkaloid derivatives have been widely concerned for their anti-tumor, anti-viral …

Masters of Mediation: MN(SiMe3)2 in Functionalization of C(sp3)−H Latent Nucleophiles

R Sreedharan, T Gandhi - Chemistry–A European Journal, 2024 - Wiley Online Library
Organoalkali compounds have undergone a far‐reaching transformation being a coupling
partner to a mediator in unusual organic conversions which finds its spot in the field of …

Design, Synthesis, and Study of the Dual Action Mode of Novel N-Thienyl-1,5-disubstituted-4-pyrazole Carboxamides against Nigrospora oryzae

C Zhang, C Zhao, H Zheng, L Li… - Journal of Agricultural …, 2023 - ACS Publications
Due to the single target but extensive application of commercialized succinate
dehydrogenase inhibitors (SDHIs), resistance problems have gradually become apparent in …

Discovery of aryloxy-, arylthio-, and arylamino-containing acethydrazides as fungicidal agents

H Fang, Z Chen, Y Liu, T Zhang, J Chang… - Journal of Agricultural …, 2022 - ACS Publications
The development of new green fungicides is an effective way to solve the resistance of
agricultural pathogens and plays an important role in promoting high-quality and …

Suzuki–Miyaura Cross-Coupling of 2-Pyridyl Trimethylammonium Salts by N–C Activation Catalyzed by Air-and Moisture-Stable Pd–NHC Precatalysts: Application to …

Y Hu, Y Gao, J Ye, Z Ma, J Feng, X Liu, P Lei… - Organic …, 2023 - ACS Publications
We report the first Suzuki–Miyaura cross-coupling of 2-pyridyl ammonium salts by highly
selective N–C activation catalyzed by air-and moisture-stable Pd (II)–NHC (NHC= N …

Straightforward synthesis of N-arylindoles via one-pot Fischer indolisation–indole N-arylation

M Lintott, A Perry - RSC advances, 2023 - pubs.rsc.org
A microwave-promoted, one-pot, three-component synthesis of N-arylindoles has been
developed, utilising sequential Fischer indolisation then copper (I)-catalysed indole N …

Synthesis of indoles via domino reactions of 2-methoxytoluene and nitriles

S Kou, J Huo, Y Wang, S Sun, F Xue… - The Journal of …, 2022 - ACS Publications
2-Arylindoles are privileged structures widely present in biologically active molecules. New
sustainable synthetic routes toward their synthesis are, therefore, in high demand. Herein, a …

LiN(SiMe3)2/KOtBu-Promoted Synthesis of Isoquinolone Derivatives from 2-Methylaryl Aldehydes and Nitriles

P Ma, Y Wang, J Wang, N Ma - The Journal of Organic Chemistry, 2023 - ACS Publications
A convenient method is proposed for the synthesis of isoquinolone derivatives from 2-
methylaryl aldehydes and nitriles through LiN (SiMe3) 2/KO t Bu-promoted formal [4+ 2] …

Synthesis of Homoallylamines Enabled by Cobalt or Palladium Catalyzed Allylic Substitution of Azaarylmethylamines

J Zheng, R Hua, YE Wang, T Lin, M Ou, Y Wu… - Organic …, 2024 - ACS Publications
Pd (OAc) 2/Nixantphos or CoI2/Nixantphos catalyzed allylic substitutions with weakly acidic
C (sp) 3–H bonds of azaarylmethylamines are described. This method facilitates access to …

A Tandem Madelung Indole Synthesis Mediated by a LiN(SiMe3)2/CsF System

R Ma, YE Wang, D Xiong, J Mao - Organic Letters, 2023 - ACS Publications
A tandem Madelung indole synthesis by the reaction of methyl benzoate and N-methyl-o-
toluidine has been discovered. The combination of LiN (SiMe3) 2 with CsF is the key factor …