The majority of exchanges of oxygen and nutrients are performed around vessels smaller
than 100 μm, allowing cells to thrive everywhere in the body. Pathologies such as cancer …

The field of super-resolution ultrasound microvascular imaging has been rapidly growing
over the past decade. By leveraging contrast microbubbles as point targets for localization …

Aging-related cognitive decline is an emerging health crisis; however, no established
unifying mechanism has been identified for the cognitive impairments seen in an aging …

Non-invasive detection of microvascular alterations in deep tissues in vivo provides critical
information for clinical diagnosis and evaluation of a broad-spectrum of pathologies …

Ultrasound Localization Microscopy (ULM) can resolve the microvascular bed down to a few
micrometers. To achieve such performance, microbubble contrast agents must perfuse the …

The resolution of an imaging system is usually determined by the width of its point spread
function and is measured using the Rayleigh criterion. For most system, it is in the order of …

Ultrasound localization microscopy is a super-resolution imaging technique that exploits the
unique characteristics of contrast microbubbles to side-step the fundamental trade-off …

Increasing evidence has suggested a link between cerebrovascular disease and the
cognitive impairment associated with Alzheimer's disease. However, detailed descriptions of …

Super-resolution ultrasound imaging (SRUS) enables in vivo microvascular imaging of
deeper-lying tissues and organs, such as the kidneys or liver. The technique allows new …

Microvascular structure and hemodynamics are important indicators for the diagnosis and
assessment of many diseases and pathologies. The structural and functional imaging of …