Small ruminant lentiviruses (SRLV) cause a multisystemic chronic disease affecting animal
production and welfare. SRLV infections are spread across the world with the exception of …

Virus-specific T-cell immune responses are important in restraint of human
immunodeficiency virus type 1 (HIV-1) replication and control of disease. Plasma viral load …

Recent worldwide serological and genetic studies of small ruminant lentiviruses (SRLV)
have led to the description of new genotypes and the development of new diagnostic tests …

Lentiviruses (a subfamily of the retroviridae family) include primate and nonprimate
viruses associated with chronic diseases of the immune system and the central nervous …

We report the identification of a new simian immunodeficiency virus (SIV), designated
SIVden, in a naturally infected Dent's Mona monkey (Cercopithecus mona denti), which was …

Lentiviruses infect both dividing CD4+ T cells and nondividing myeloid cells, and the
infected myeloid cells serve as long-living viral reservoirs. Host sterile alpha motif–and …

The innate immune restriction factor SAMHD1 can inhibit diverse viruses in myeloid cells.
Mechanistically, SAMHD1 inhibits lentiviral replication including HIV-1 by depleting the …

Background Treatment of feline immunodeficiency virus (FIV) infection has been hampered
by the absence of a specific combination antiretroviral treatment (ART). Integrase strand …

Small ruminant lentiviruses (SRLVs) are widespread and infect goats and sheep. Several
reports also suggest that SRLVs can infect wild ruminants. The presence of specific …

Abstract In 1936, John Joseph Bittner identified mouse mammary tumor virus (MMTV), a milk
transmitted beta retrovirus, a form of single-stranded positive-sense RNA virus. A retrovirus …