Biofilms in chronic wounds: pathogenesis and diagnosis

YK Wu, NC Cheng, CM Cheng - Trends in biotechnology, 2019 - cell.com
Chronic non-healing wounds have become a major worldwide healthcare burden. The
impact of biofilms on chronic wound infection is well established. Despite increasing …

Biofilms in diabetic foot ulcers: Significance and clinical relevance

C Pouget, C Dunyach-Remy, A Pantel, S Schuldiner… - Microorganisms, 2020 - mdpi.com
Foot infections are the main disabling complication in patients with diabetes mellitus. These
infections can lead to lower-limb amputation, increasing mortality and decreasing the quality …

In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment

J Ouyang, X Ji, X Zhang, C Feng… - Proceedings of the …, 2020 - National Acad Sciences
The treatment of diabetic ulcer (DU) remains a major clinical challenge due to the complex
wound-healing milieu that features chronic wounds, impaired angiogenesis, persistent pain …

Dissolvable Microneedles Coupled with Nanofiber Dressings Eradicate Biofilms via Effectively Delivering a Database-Designed Antimicrobial Peptide

Y Su, VL Mainardi, H Wang, A McCarthy, YS Zhang… - ACS …, 2020 - ACS Publications
Biofilms in chronic wounds, including diabetic foot ulcers, pressure ulcers, and venous leg
ulcers, pose a major challenge to wound management. Herein, we report a Janus-type …

[PDF][PDF] IWGDF guidance on the diagnosis and management of foot infections in persons with diabetes

BA Lipsky, J Aragón-Sánchez, M Diggle… - Diabetes Metab Res …, 2016 - aogp.com.au
23. Do not select a specific type of dressing for a diabetic foot infection with the aim of
preventing an infection or improving its outcome (strong; high). 24. For diabetic foot …

Chronic wound infections: the role of Pseudomonas aeruginosa and Staphylococcus aureus

R Serra, R Grande, L Butrico, A Rossi… - Expert review of anti …, 2015 - Taylor & Francis
Chronic leg ulcers affect 1–2% of the general population and are related to increased
morbidity and health costs. Staphylococcus aureus and Pseudomonas aeruginosa are the …

Bacterial contribution in chronicity of wounds

K Rahim, S Saleha, X Zhu, L Huo, A Basit, OL Franco - Microbial ecology, 2017 - Springer
A wound is damage of a tissue usually caused by laceration of a membrane, generally the
skin. Wound healing is accomplished in three stages in healthy individuals, including …

2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections

BA Lipsky, AR Berendt, PB Cornia… - Clinical infectious …, 2012 - academic.oup.com
Foot infections are a common and serious problem in persons with diabetes. Diabetic foot
infections (DFIs) typically begin in a wound, most often a neuropathic ulceration. While all …

Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified

M De Angelis, M Piccolo, L Vannini, S Siragusa… - PloS one, 2013 - journals.plos.org
This study aimed at investigating the fecal microbiota and metabolome of children with
Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) and autism (AD) in …

Living in your skin: microbes, molecules, and mechanisms

MH Swaney, LR Kalan - Infection and immunity, 2021 - Am Soc Microbiol
Human skin functions as a physical, chemical, and immune barrier against the external
environment while also providing a protective niche for its resident microbiota, known as the …