Glomerular epithelial cells, podocytes, are insulin responsive and can develop insulin
resistance. Here, we demonstrate that the small GTPase septin 7 forms a complex with …

Tankyrase 1 and 2, members of the poly (ADP-ribose) polymerase family, have previously
been shown to play a role in insulin-mediated glucose uptake in adipocytes. However, their …

Foraging disruption caused by human activities is emerging as a key issue in cetacean
conservation because it can affect nutrient levels and the amount of energy available to …

Mung beans are among the important edible legumes cultivated in Asia, Southern Europe,
and Northern America. Mung beans contain 20–30% proteins with high digestibility and …

Insulin increases glucose uptake and storage in muscle and adipose cells, which is
accomplished through the mobilization of intracellular GLUT4 storage vesicles (GSVs) to the …

Eukaryotic plasma membrane (PM) transporters face critical challenges that are not widely
present in prokaryotes. The two most important issues are proper subcellular traffic and …

Diabetes mellitus (DM) is a significant public health problem. Diabetic kidney disease (DKD)
is the most common complication of DM, and its incidence has been increasing with the …

Hyperglycemia results in accumulation of the reactive dicarbonyl methylglyoxal (MG).
Methylglyoxal is detoxified by the glyoxalase system (glyoxalase 1 and 2). The influence of …

Abstract Phosphatidylinositol‐3'‐kinases (PI3Ks) are a family of lipid kinases that
phosphorylate the 3'hydroxyl (OH) of the inositol ring of phosphatidylinositides (PI). Through …

Mutations within Leucine-rich repeat kinase 2 (LRRK2) are associated with late-onset
Parkinson's disease. The physiological function of LRRK2 and molecular mechanism …