[PDF][PDF] Utility of microscopic observation of drug susceptibility (MODS) assay for Mycobacterium tuberculosis in resource constrained settings

K Limaye, S Kanade, G Nataraj, P Mehta - Indian J Tuberc, 2010 - academia.edu
Summary Introduction: Multidrug Resistant Tuberculosis (MDR TB) is a global health
problem. Conventional techniques or automated systems for diagnosis and drug …

Evaluation of microscopic observation drug susceptibility assay for diagnosis of multidrug-resistant Tuberculosis in Viet Nam

DT Minh Ha, NT Ngoc Lan, M Wolbers, VS Kiet… - BMC infectious …, 2012 - Springer
Background Early diagnosis of tuberculosis (TB) and multidrug resistant tuberculosis (MDR
TB) is important for the elimination of TB. We evaluated the microscopic observation drug …

[PDF][PDF] Introducing MODS: a low-cost, low-tech tool for high-performance detection of tuberculosis and multidrug resistant tuberculosis

L Caviedes, DA Moore - Indian J Med Microbiol, 2007 - modsperu.org
The urgent need for improved diagnostic tools for detection of tuberculosis (TB) and
multidrug resistant tuberculosis (MDRTB) has been repeatedly highlighted. It is patently …

Development of Low-Cost Inverted Microscope to Detect Early Growth of Mycobacterium tuberculosis in MODS Culture

M Zimic, A Velazco, G Comina, J Coronel, P Fuentes… - PLoS one, 2010 - journals.plos.org
Background The microscopic observation drug susceptibility (MODS) assay for rapid, low-
cost detection of tuberculosis and multidrug resistant tuberculosis depends upon …

Second-line drug susceptibility breakpoints for Mycobacterium tuberculosis using the MODS assay

AP Trollip, D Moore, J Coronel… - … of tuberculosis and …, 2014 - ingentaconnect.com
OBJECTIVE: To establish breakpoint concentrations for the fluoroquinolones (moxifloxacin
[MFX] and ofloxacin [OFX]) and injectable second-line drugs (amikacin [AMK], kanamycin …

Prospective evaluation of simply modified MODS assay: an effective tool for TB diagnosis and detection of MDR-TB

B Chaiyasirinroje, MN Aung, S Moolphate… - Infection and drug …, 2012 - Taylor & Francis
Background and setting Thailand is one of the highest tuberculosis (TB)-burdened countries.
Chiang Rai, the northernmost province of Thailand has high tuberculosis and human …

Tuberculosis and HIV–needed: a new paradigm for the control and management of linked epidemics

SJ Tsiouris, NR Gandhi, WM El-Sadr… - Journal of the International …, 2007 - Springer
Tuberculosis (TB) and human immunodeficiency virus (HIV) disease have been closely
entwined since the early years of the HIV/AIDS pandemic. The 2 conditions overlap in their …

Second-line anti-tuberculosis drug concentrations for susceptibility testing in the MODS assay

SP Fitzwater, GA Sechler, O Jave… - European …, 2013 - Eur Respiratory Soc
Multidrug-resistant tuberculosis (TB) threatens TB control worldwide. The microscopic
observation drug susceptibility (MODS) assay is a low-cost, high-performance TB diagnostic …

A quantitative adaptation of the Wayne test for pyrazinamide resistance

C Meinzen, A Proaño, RH Gilman, L Caviedes… - Tuberculosis, 2016 - Elsevier
Background Pyrazinamide (PZA) is the most important drug against the latent stage of
tuberculosis (TB) and is used in both first and second line treatment regimens. The …

Antimicrobial resistance in tuberculosis: an international perspective

PD Van Helden, PR Donald, TC Victor… - Expert Review of Anti …, 2006 - Taylor & Francis
Drug-resistant tuberculosis is a threat to tuberculosis control programs and community
health. This growing problem mirrors the increasing incidence of tuberculosis in general …