Alopecia areata: an update on etiopathogenesis, diagnosis, and management
C Zhou, X Li, C Wang, J Zhang - Clinical Reviews in Allergy & …, 2021 - Springer
Alopecia areata (AA) is a common chronic tissue-specific autoimmune disease, resulting in
hair loss, that affects up to 2% of the general population. The exact pathobiology of AA has …
hair loss, that affects up to 2% of the general population. The exact pathobiology of AA has …
[HTML][HTML] Dupilumab in inflammatory skin diseases: a systematic review
Dupilumab was first approved for the treatment of atopic dermatitis (AD) and blocks the
signaling of interleukin (IL)-4 and-13. Several other chronic skin conditions share …
signaling of interleukin (IL)-4 and-13. Several other chronic skin conditions share …
Phase 2a randomized clinical trial of dupilumab (anti‐IL‐4Rα) for alopecia areata patients
E Guttman‐Yassky, Y Renert‐Yuval, J Bares… - Allergy, 2022 - Wiley Online Library
Background Treatments for alopecia areata (AA) patients with extensive scalp hair loss are
limited, and recent evidence supports a role for type 2 T‐cell (Th2)‐immune response in AA …
limited, and recent evidence supports a role for type 2 T‐cell (Th2)‐immune response in AA …
Alopecia areata–Current understanding and management
DA Lintzeri, A Constantinou, K Hillmann… - JDDG: Journal der …, 2022 - Wiley Online Library
Alopecia areata (AA) is a chronic, immune‐mediated disease characterized by acute or
chronic non‐scarring hair loss, with a heterogeneity in clinical manifestations ranging from …
chronic non‐scarring hair loss, with a heterogeneity in clinical manifestations ranging from …
Hair follicle melanocytes initiate autoimmunity in alopecia areata: a trigger point
B Xie, J Sun, X Song - Clinical Reviews in Allergy & Immunology, 2022 - Springer
Alopecia areata (AA) is characterized by common non-scarring alopecia due to autoimmune
disorders. To date, the specific pathogenesis underlying AA remains unknown. Thus, AA …
disorders. To date, the specific pathogenesis underlying AA remains unknown. Thus, AA …
[HTML][HTML] A literature review of real-world effectiveness and safety of dupilumab for atopic dermatitis
M Kamata, Y Tada - JID Innovations, 2021 - Elsevier
Atopic dermatitis (AD) is a chronic inflammatory skin disease with pruritus, characterized by
recurrent eczema with exacerbations and remissions. AD impairs patients' QOL and places …
recurrent eczema with exacerbations and remissions. AD impairs patients' QOL and places …
[HTML][HTML] Association of atopic dermatitis with autoimmune diseases: A bidirectional and multivariable two-sample mendelian randomization study
W Zhou, J Cai, Z Li, Y Lin - Frontiers in Immunology, 2023 - frontiersin.org
Background Observational studies have suggested the association between atopic
dermatitis (AD) and the risks of autoimmune diseases. It is still unclear, however, whether or …
dermatitis (AD) and the risks of autoimmune diseases. It is still unclear, however, whether or …
Scalp biomarkers during dupilumab treatment support Th2 pathway pathogenicity in alopecia areata
Y Renert‐Yuval, AB Pavel, E Del Duca, P Facheris… - Allergy, 2023 - Wiley Online Library
Background The mechanisms driving alopecia areata (AA) are still unclear, hindering
development of targeted therapeutics. Specific Th2 targeting with dupilumab in AA provides …
development of targeted therapeutics. Specific Th2 targeting with dupilumab in AA provides …
Systematic review of newer agents for the management of alopecia areata in adults: Janus kinase inhibitors, biologics and phosphodiesterase‐4 inhibitors
AK Gupta, T Wang, S Polla Ravi… - Journal of the …, 2023 - Wiley Online Library
Management options for moderate‐to‐severe alopecia areata (AA) are limited owing to a
lack of safe and effective treatments suitable for long‐term use. However, newer agents …
lack of safe and effective treatments suitable for long‐term use. However, newer agents …
Dupilumab therapy for alopecia areata in pediatric patients with concomitant atopic dermatitis
PL McKenzie, L Castelo-Soccio - Journal of the American …, 2021 - pubmed.ncbi.nlm.nih.gov
Dupilumab therapy for alopecia areata in pediatric patients with concomitant atopic dermatitis
Dupilumab therapy for alopecia areata in pediatric patients with concomitant atopic dermatitis J …
Dupilumab therapy for alopecia areata in pediatric patients with concomitant atopic dermatitis J …