Thrombosis is the underlying cause of a host of common, debilitating, and often fatal
cardiovascular disorders. Formation of thrombi in the arterial circulation can lead to acute …

Thalidomide is a teratogenic/hypnotic/sedative agent which elicits a wide range of
pharmaceutical/biological activities. The diversity of its biological activities suggested that …

Indolines are important moieties present in various biologically significant molecules and
have attracted considerable attention in synthetic chemistry. This paper describes a Heck …

This paper describes the syntheses of several functionalized dihydropyrene (DHP)
molecular switches with different substitution patterns. Regioselective nucleophilic alkylation …

We have developed an efficient Brønsted acid-controlled strategy for the [3+ 2] coupling
reaction of quinone monoacetals (QMAs) with nucleophilic alkenes, which is triggered by the …

Thromboembolic diseases are the leading causes of morbidity and mortality in the
developed world. Anticoagulants provide effective treatment for venous or arterial …

Abstract Since 1, 4‐epoxy‐1, 4‐dihydronaphthalenes are smoothly converted to 1‐naphthol
derivatives via unstable cation intermediates formed by the acid‐catalyzed ring‐opening …

A series of cinnamylindoline derivatives were synthesized, and their factor Xa (FXa)
inhibitory activities and selectivity over trypsin were evaluated. Among them, some novel …

To develop a novel and effective anticoagulant with potent and selective factor Xa (FXa)
inhibitory activity, a new series of cinnamyl derivatives with enhanced lipophilicity and …

The reaction of indoline with a substituted benzoyl chloride in the presence of K2CO3 in THF
gave compound 4. Compound 4 was subjected to chlorosulphonation to obtain compound …