Neurobiology of depression in Parkinson's disease: Insights into epidemiology, molecular mechanisms and treatment strategies

MH Ahmad, MA Rizvi, M Ali, AC Mondal - Ageing research reviews, 2023 - Elsevier
Parkinson's disease (PD) is characterized mainly by motor dysfunctions due to the
progressive loss of dopaminergic neurons. However, PD patients experience a multitude of …

The relationship between 5-hydroxytryptamine and its metabolite changes with post-stroke depression

S Gu, Z He, Q Xu, J Dong, T Xiao, F Liang, X Ma… - Frontiers in …, 2022 - frontiersin.org
Post-stroke depression (PSD) is the most common and serious sequelae of stroke.
Approximately 33% of stroke survivors were affected by PSD. However, many issues (eg …

Propofol exerts anti-anhedonia effects via inhibiting the dopamine transporter

XN Zhu, J Li, GL Qiu, L Wang, C Lu, YG Guo, KX Yang… - Neuron, 2023 - cell.com
Lasker's award-winning drug propofol is widely used in general anesthesia. The
recreational use of propofol is reported to produce a well-rested feeling and euphoric state; …

Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice

Y Ni, Y Feng, D Shen, M Chen, X Zhu, Q Zhou… - Journal of …, 2022 - Springer
Abstract Background Anti-IgLON5 disease is a rare neurological disorder associated with
autoantibodies against the neuronal cell adhesion protein, IgLON5. Cellular investigations …

Antidepressant-like Activity of Patchouli Oil var. Tapak Tuan (Pogostemon cablin Benth) via Elevated Dopamine Level: A Study Using Rat Model

P Astuti, K Khairan, M Marthoenis, K Hasballah - Pharmaceuticals, 2022 - mdpi.com
Essential oils are gaining popularity for their use in treating depression, including that
extracted from patchouli leaves and stems (Pogostemon cablin). Herein, we used patchouli …

Cell-type-specific imaging of neurotransmission reveals a disrupted excitatory-inhibitory cortical network in isoflurane anaesthesia

J Guo, M Ran, Z Gao, X Zhang, D Wang, H Li, S Zhao… - …, 2021 - thelancet.com
Background Despite the fundamental clinical significance of general anaesthesia, the
cortical mechanism underlying anaesthetic-induced loss of consciousness (aLOC) remains …

Efficacy, safety, and tolerability of serotonin-norepinephrine reuptake inhibitors in controlling ADHD symptoms: a systematic review and meta-analysis

RA Dezfouli, A Hosseinpour, S Ketabforoush… - Middle East Current …, 2024 - Springer
Introduction The aim of this study is to assess the effectiveness of serotonin-norepinephrine
reuptake inhibitors (SNRIs) in managing ADHD symptoms compared to placebo, stimulants …

Prediction of early improvement of major depressive disorder to antidepressant medication in adolescents with radiomics analysis after ComBat harmonization based …

H Ma, D Zhang, Y Wang, Y Ding, J Yang, K Li - BMC psychiatry, 2023 - Springer
Background Due to individual differences and lack of objective biomarkers, only 30-40%
patients with major depressive disorder (MDD) achieve remission after initial antidepressant …

The effect and safety of probiotics on depression: a systematic review and meta-analysis of randomized controlled trials

J Lin, Y Zhang, K Wang, J Wang, S Kou, K Chen… - European Journal of …, 2023 - Springer
Purpose With the escalating social pressures, there has been a continuous rise in the
prevalence of depression among the population, leading to substantial healthcare burdens …

Purified serum IgG from a patient with Anti-IgLON5 antibody cause long-term movement disorders with impaired dopaminergic pathways in mice

Y Gao, H Li, H Luo, Y Ni, Y Feng, L He, Q Zhou, J Hu… - Biomedicines, 2023 - mdpi.com
Background: Anti-IgLON5 disease is a rare autoimmune disease of the central nervous
system. It typically manifests as a chronic condition, characterized by cognitive impairments …