Understanding mechanisms of antioxidant action in health and disease

B Halliwell - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Several different reactive oxygen species (ROS) are generated in vivo. They have roles in
the development of certain human diseases whilst also performing physiological functions …

Molecular probes for autofluorescence-free optical imaging

Y Jiang, K Pu - Chemical reviews, 2021 - ACS Publications
Optical imaging is an indispensable tool in clinical diagnostics and fundamental biomedical
research. Autofluorescence-free optical imaging, which eliminates real-time optical …

MOF based electrochemical sensors for the detection of physiologically relevant biomolecules: An overview

M Daniel, G Mathew, M Anpo, B Neppolian - Coordination Chemistry …, 2022 - Elsevier
It is known that biomolecules are physiologically significant in controlling homeostasis. Any
deviation in homeostasis is often detected by a change in the concentrations of these …

Antioxidants and antioxidant methods: An updated overview

İ Gulcin - Archives of toxicology, 2020 - Springer
Antioxidants had a growing interest owing to their protective roles in food and
pharmaceutical products against oxidative deterioration and in the body and against …

Copper-based metal–organic frameworks for biomedical applications

JE Cun, X Fan, Q Pan, W Gao, K Luo, B He… - Advances in Colloid and …, 2022 - Elsevier
Metal–organic frameworks (MOFs) are a class of important porous, crystalline materials
composed of metal ions (clusters) and organic ligands. Owing to the unique redox chemistry …

Supramolecular polymerization‐induced nanoassemblies for self‐augmented cascade chemotherapy and chemodynamic therapy of tumor

K Yang, G Yu, Z Yang, L Yue, X Zhang… - Angewandte Chemie …, 2021 - Wiley Online Library
The clinical application of chemodynamic therapy is impeded by the insufficient intracellular
H2O2 level in tumor tissues. Herein, we developed a supramolecular nanoparticle via a …

Cu-MOF chemodynamic nanoplatform via modulating glutathione and H2O2 in tumor microenvironment for amplified cancer therapy

H Tian, M Zhang, G Jin, Y Jiang, Y Luan - Journal of Colloid and Interface …, 2021 - Elsevier
Chemodynamic therapy (CDT) utilizes Fenton catalysts to convert intracellular hydrogen
peroxide (H 2 O 2) into cytotoxic hydroxyl radical (OH∙) for tumor therapy, but endogenous H …

[HTML][HTML] Chemistry of hydrogen peroxide formation and elimination in mammalian cells, and its role in various pathologies

CMC Andrés, JM Pérez de la Lastra, CA Juan, FJ Plou… - Stresses, 2022 - mdpi.com
Hydrogen peroxide (H2O2) is a compound involved in some mammalian reactions and
processes. It modulates and signals the redox metabolism of cells by acting as a messenger …

Flexible sensors for hydrogen peroxide detection: A critical review

JE Giaretta, H Duan, F Oveissi… - … Applied Materials & …, 2022 - ACS Publications
Hydrogen peroxide (H2O2) is a common chemical used in many industries and can be
found in various biological environments, water, and air. Yet, H2O2 in a certain range of …

Development of multifunctional molecules as potential therapeutic candidates for Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis in the …

MG Savelieff, G Nam, J Kang, HJ Lee, M Lee… - Chemical …, 2018 - ACS Publications
Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …