The recognition that schizophrenia is a disorder of neurodevelopment is widely accepted.
The original hypothesis was coined more than 30 years ago and the wealth of supportive …

Maternal immune activation (MIA) during pregnancy is recognized as an etiological risk
factor for various psychiatric disorders, such as schizophrenia, major depressive disorder …

Background The bidirectional communication between neurons and microglia is
fundamental for the homeostasis and biological function of the central nervous system …

Background: Schizophrenia is a serious mental illness that affects more than 21 million
people worldwide. Both genetics and the environment play a role in its etiology and …

Multiple lines of evidence support the pathogenic role of maternal immune activation (MIA)
in the occurrence of the schizophrenia-like disturbances in offspring. While in the brain the …

Early life challenges resulting from maternal immune activation (MIA) may exert persistent
effects on the offspring, including the development of psychiatric disorders, such as …

In her 1936 report of paired-pulse blink inhibition in 13 Yale undergraduate men, Helen
Peak described “quantitative variation in amount of inhibition of the second response …

A combination of genetic and environmental risk factors has been considered as the
pathogenic cause for mental disorders including schizophrenia. Here, we sought to find out …

Objective Many hypotheses have put forward to better understand the pathogenesis of
schizophrenia (SZ), such as synaptic pruning, stress-diathesis, neurodevelopment …

Repeated early environmental deprivation is regarded as a typical paradigm to mimic the
behavioral abnormalities and brain dysfunction that occur in psychiatric disorders …