Effects of ionizing radiation on biological molecules—mechanisms of damage and emerging methods of detection

JA Reisz, N Bansal, J Qian, W Zhao… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: The detrimental effects of ionizing radiation (IR) involve a highly orchestrated
series of events that are amplified by endogenous signaling and culminating in oxidative …

New advances in separation science for metabolomics: resolving chemical diversity in a post-genomic era

NL Kuehnbaum, P Britz-McKibbin - Chemical reviews, 2013 - ACS Publications
Metabolomics offers a revolutionary framework for phenotyping individuals at a molecular
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …

Challenges and opportunities of metabolomics

CH Johnson, FJ Gonzalez - Journal of cellular physiology, 2012 - Wiley Online Library
The metabolome is a data‐rich source of information concerning all the low‐molecular‐
weight metabolites in a biofluid, which can indicate early biological changes to the host due …

Capillary electrophoresis–electrospray ionization-mass spectrometry interfaces: Fundamental concepts and technical developments

G Bonvin, J Schappler, S Rudaz - Journal of Chromatography A, 2012 - Elsevier
Capillary electrophoresis (CE) hyphenated to electrospray ionization (ESI) mass
spectrometry (MS) is a powerful tool for analyzing a wide variety of analytes in different …

CE‐MS for metabolomics: Developments and applications in the period 2010–2012

R Ramautar, GW Somsen, GJ de Jong - Electrophoresis, 2013 - Wiley Online Library
CE‐MS has emerged as a powerful technique for the profiling of (highly) polar and charged
metabolites in biological samples. This review provides an update of the most recent …

Capillary electrophoresis

M Geiger, AL Hogerton, MT Bowser - Analytical Chemistry, 2012 - ACS Publications
Capillary electrophoresis (CE) is a field that continues to grow. All areas of CE including
theory, separation modes, instrumentation, and applications remain highly active areas of …

Capillary electrophoresis as a metabolomics tool for non-targeted fingerprinting of biological samples

C Barbas, EP Moraes, A Villasenor - Journal of pharmaceutical and …, 2011 - Elsevier
Metabolomics, understood as a data driven strategy trying to find markers of a situation
under study without a priori hypothesis, has rapidly caught the attention and evolved from …

An extremely radioresistant green eukaryote for radionuclide bio-decontamination in the nuclear industry

C Rivasseau, E Farhi, A Atteia, A Couté… - Energy & …, 2013 - pubs.rsc.org
Nuclear activities generate radioactive elements which require processes for their
decontamination. Although biological remediation has proved to be efficient in industrial …

[HTML][HTML] Radiation metabolomics: current status and future directions

SS Menon, M Uppal, S Randhawa, MS Cheema… - Frontiers in …, 2016 - frontiersin.org
Human exposure to ionizing radiation (IR) disrupts normal metabolic processes in cells and
organs by inducing complex biological responses that interfere with gene and protein …

[HTML][HTML] CD47 receptor globally regulates metabolic pathways that control resistance to ionizing radiation

TW Miller, DR Soto-Pantoja, AL Schwartz… - Journal of Biological …, 2015 - ASBMB
Modulating tissue responses to stress is an important therapeutic objective. Oxidative and
genotoxic stresses caused by ionizing radiation are detrimental to healthy tissues but …