Inactivation of cysteine 674 in the SERCA2 accelerates experimental aortic aneurysm
Y Que, X Shu, L Wang, P Hu, S Wang, R Xiong… - Journal of Molecular and …, 2020 - Elsevier
Abstract Sarcoplasmic/endoplasmic reticulum Ca 2+ ATPase 2 (SERCA2) is vital to maintain
intracellular calcium homeostasis. SERCA2 cysteine 674 (C674) is highly conservative and …
intracellular calcium homeostasis. SERCA2 cysteine 674 (C674) is highly conservative and …
[HTML][HTML] Tongxinluo promotes endothelium-dependent arteriogenesis to attenuate diabetic peripheral arterial disease
JJ Gu, YL Hou, YH Yan, J Li, YR Wei, K Ma… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Peripheral arterial disease (PAD) has become one of the leading causes of
disa-bility and death in diabetic patients. Restoring blood supply to the hindlimbs, especially …
disa-bility and death in diabetic patients. Restoring blood supply to the hindlimbs, especially …
Macrophages aggravate hypoxia-induced cardiac microvascular endothelial cell injury via peroxynitrite: protection by tongxinluo
X Wang, K Liu, B Li, Y Li, K Ye, J Qi… - Cell communication & …, 2015 - Taylor & Francis
Activated macrophages contribute to endothelial dysfunction; however, it is unclear how
peroxynitrite contributes to macrophage-mediated human cardiac microvascular endothelial …
peroxynitrite contributes to macrophage-mediated human cardiac microvascular endothelial …
[HTML][HTML] Role of endoplasmic reticulum oxidase 1α in H9C2 cardiomyocytes following hypoxia/reoxygenation injury
L Lai, Y Liu, Y Liu, N Zhang… - Molecular …, 2020 - spandidos-publications.com
Endoplasmic reticulum (ER) oxidase 1α (ERO1α) is a glycosylated flavoenzyme that is
located on the luminal side of the ER membrane, which serves an important role in …
located on the luminal side of the ER membrane, which serves an important role in …
[HTML][HTML] Naoluo Xintong capsule ameliorates apoptosis induced by endoplasmic reticulum stress in rats with cerebral ischemia/reperfusion injury
S Wu, X Piao, N Wang, Y Zhai - Annals of Palliative Medicine, 2020 - apm.amegroups.org
Background: Naoluo Xintong (NLXT) capsuleis a newly developed drug recorded in the
Chinese Pharmacopoeia. It is derived from traditional Chinese medicine (TCM) NLXT …
Chinese Pharmacopoeia. It is derived from traditional Chinese medicine (TCM) NLXT …
Angiotensin Receptor Blocker and Neprilysin Inhibitor Suppresses Cardiac Dysfunction by Accelerating Myocardial Angiogenesis in Apolipoprotein E-Knockout Mice …
Y Suematsu, K Tashiro, H Morita… - Journal of the Renin …, 2021 - journals.sagepub.com
Hypothesis. Myocardial angiogenesis is important for maintaining cardiac contractile
function in patients with cardiac hypertrophy. Evidence shows that angiotensin receptor …
function in patients with cardiac hypertrophy. Evidence shows that angiotensin receptor …
The vasodilatory effect of gemigliptin via activation of voltage-dependent K+ channels and SERCA pumps in aortic smooth muscle
HS Jung, MS Seo, JR An, M Kang, R Heo, H Li… - European Journal of …, 2020 - Elsevier
This study investigated the vasodilatory effects and acting mechanism of gemigliptin, a
dipeptidyl peptidase-4 (DPP-4) inhibitor. Tests were conducted in aortic rings pre-contracted …
dipeptidyl peptidase-4 (DPP-4) inhibitor. Tests were conducted in aortic rings pre-contracted …
Substitution of the SERCA2 Cys674 reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation
H Su, Y Mei, S Luo, H Wu, Y He… - British Journal of …, 2022 - Wiley Online Library
Background and Purpose The cysteine674 (C674) thiol of sarcoplasmic/endoplasmic
reticulum Ca2+ ATPase 2 is easily and irreversibly oxidized under atherosclerotic …
reticulum Ca2+ ATPase 2 is easily and irreversibly oxidized under atherosclerotic …
Influence of a bearing-wastewater phenolic compound (3,4-dimethylphenol, 3,4-DMP) treatment on Ca2+ homeostasis and its related cytotoxicity in human proximal …
KJ Cheng, WZ Liang - Human & Experimental Toxicology, 2021 - journals.sagepub.com
A lot of phenolic compounds are widespread in industrial effluents and they are
considerable environmental pollutants. Being a compound commercially available, the effect …
considerable environmental pollutants. Being a compound commercially available, the effect …