Despite the prevalence of depression in lactating mothers, there is a lack of knowledge
about the excretion of antidepressants into breast milk and its potential adverse effects on …

Abstract Cannabis, cocaine, 3, 4-methylenedioxymethamphetamine, and lysergic acid
diethylamide are psychoactive substances with a significant increase in consumption during …

Humans are constantly exposed to lipophilic persistent organic pollutants (POPs) that
accumulate in fatty foods. Among the numerous POPs, dioxins, in particular 2, 3, 7, 8 …

Abstract Characterization of infant drug exposure through human milk is important and
underexplored. Because infant plasma concentrations are not frequently collected in clinical …

The development of an effective method for predicting the transfer of biologics from plasma
into breast milk is important to ensure the safe use of medications during lactation. The aim …

Determining the amount of a drug transferred into breast milk is critical for benefit-risk
analysis of breastfeeding when a lactating mother takes medications. In this study, we …

The article reports that several organizations such as the American Academy of Pediatrics,
World Health Organization and Centers for Disease Control and Prevention recommend …

Lack of data on drug secretion in human milk is a concern for safe use of drugs during
postpartum. Clinical studies are often difficult to perform; despite substantial improvements …

In 1990, Atkinson and Begg developed a set of prediction equations to estimate milk plasma
ratios (M/P) of small molecules based on the physicochemical and pharmacokinetic …

The phase distribution model, proposed by Atkinson and Begg in 1990, has been widely
used for predicting breastmilk‐to‐plasma drug concentration ratio. However …