NLRP3 inflammasome and inflammatory diseases

Z Wang, S Zhang, Y Xiao, W Zhang… - Oxidative medicine …, 2020 - Wiley Online Library
Almost all human diseases are strongly associated with inflammation, and a deep
understanding of the exact mechanism is helpful for treatment. The NLRP3 inflammasome …

New strategies for local treatment of vaginal infections

R Palmeira-de-Oliveira, A Palmeira-de-Oliveira… - Advanced drug delivery …, 2015 - Elsevier
Vaginal infections are extremely prevalent, particularly among women of reproductive age.
Although they do not result in high mortality rates, these infections are associated with high …

Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans

G Vargas, JDB Rocha, DL Oliveira… - Cellular …, 2015 - Wiley Online Library
The release of extracellular vesicles (EV) by fungal organisms is considered an alternative
transport mechanism to trans‐cell wall passage of macromolecules. Previous studies have …

[HTML][HTML] Microbial and fungal protease inhibitors—current and potential applications

J Sabotič, J Kos - Applied microbiology and biotechnology, 2012 - Springer
Proteolytic enzymes play essential metabolic and regulatory functions in many biological
processes and also offer a wide range of biotechnological applications. Because of their …

Candida and candidiasis in HIV-infected patients: where commensalism, opportunistic behavior and frank pathogenicity lose their borders

A Cassone, R Cauda - Aids, 2012 - journals.lww.com
In this era of efficacious antiretroviral therapy and consequent immune reconstitution,
oropharyngeal and esophageal candidiasis (OPC and OEC) still remain two clinically …

Phenotypic Characteristics Associated with Virulence of Clinical Isolates from the Sporothrix Complex

R Almeida-Paes, LC De Oliveira… - BioMed research …, 2015 - Wiley Online Library
The Sporothrix complex members cause sporotrichosis, a subcutaneous mycosis with a
wide spectrum of clinical manifestations. Several specific phenotypic characteristics are …

Phenotypical properties associated with virulence from clinical isolates belonging to the Candida parapsilosis complex

ÉA Abi-Chacra, LOP Souza, LP Cruz… - FEMS Yeast …, 2013 - academic.oup.com
The production of virulence attributes in three reference strains and 11 clinical isolates
primarily identified as Candida parapsilosis was evaluated. Morphological and phenotypical …

Bis 1, 2, 3‐Triazoles Linked Deoxybenzoin Hybrids as Antimicrobial Agents: Synthesis, In Vitro and In Silico Screening

S Aitha, V Thumma, S Ambala, R Matta… - …, 2023 - Wiley Online Library
A series of new deoxybenzoin based bis 1, 2, 3‐triazole analogues were synthesized and
reported in the present communication. Synthesis of analogues were accomplished by a …

Antimicrobial action of chelating agents: repercussions on the microorganism development, virulence and pathogenesis

A LS Santos, CL Sodre, RS Valle… - Current Medicinal …, 2012 - ingentaconnect.com
Infections caused by resistant microorganisms often fail to respond to conventional therapy,
resulting in prolonged illness, increased treatment costs and greater risk of death …

[HTML][HTML] Synergistic Antifungal Effect of Fluconazole Combined with Licofelone against Resistant Candida albicans

X Liu, T Li, D Wang, Y Yang, W Sun, J Liu… - Frontiers in …, 2017 - frontiersin.org
Candida albicans (C. albicans) is one of the important opportunistic fungal pathogens that is
closely associated with disseminated or chronic infections. The objective of this study is to …