There is abundant evidence that tumor-infiltrating CD8+ T cells contribute positively to
antitumor immunity; however, the role of tumor-infiltrating B cells (TIL-B) and plasma cells …

The outstanding clinical success of immune checkpoint blockade has revived the interest in
underlying mechanisms of the immune system that are capable of eliminating tumors even …

Liver cancer is the second leading cause of cancer‐related deaths, and hepatocellular
carcinoma (HCC) is the most common type. Therefore, molecular targets are urgently …

Primary liver cancer, mostly hepatocellular carcinoma, remains a difficult-to-treat cancer.
Incidence of liver cancer varies geographically and parallels with the geographic prevalence …

During their development and progression tumors acquire numerous mutations that, when
translated into proteins give rise to neoantigens that can be recognized by T cells. Initially …

Cell surface biochemical changes, notably excessive increase in outer leaflet sphingomyelin
(SM) content, are important in cancer initiation, growth, and immune evasion. Innumerable …

Hepatocellular carcinoma (HCC) is considered an immunogenic tumor that arises in
chronically inflamed livers due to underlying chronic liver disease caused by viral and non …

Background Circulating biomarkers are urgently needed in hepatocellular carcinoma (HCC).
The aims of this study were to determine the feasibility of detecting and isolating circulating …

Background: Glypican-3 (GPC3) has been widely recognized in the progression of liver
tumors for several years. The relationship between overexpression of GPC3 and the poorer …

Simple Summary Liver transplantation and surgical resection are potentially curative options
in patients with liver cirrhosis and hepatocellular carcinoma. However, tumor recurrence is …