Interleukin-1 beta as a target for atherosclerosis therapy: biological basis of CANTOS and beyond
P Libby - Journal of the American College of Cardiology, 2017 - jacc.org
Inflammatory pathways drive atherogenesis and link conventional risk factors to
atherosclerosis and its complications. One inflammatory mediator has come to the fore as a …
atherosclerosis and its complications. One inflammatory mediator has come to the fore as a …
[HTML][HTML] Neutrophil-derived cytokines: facts beyond expression
C Tecchio, A Micheletti, MA Cassatella - Frontiers in immunology, 2014 - frontiersin.org
Polymorphonuclear neutrophils, besides their involvement in primary defense against
infections–mainly through phagocytosis, generation of toxic molecules, release of enzymes …
infections–mainly through phagocytosis, generation of toxic molecules, release of enzymes …
[HTML][HTML] Anti-inflammatory potential of ellagic acid, gallic acid and punicalagin A&B isolated from Punica granatum
LA BenSaad, KH Kim, CC Quah, WR Kim… - … and alternative medicine, 2017 - Springer
Background Punica granatum (pomegranate), an edible fruit originating in the Middle East,
has been used as a traditional medicine for treatment of pain and inflammatory conditions …
has been used as a traditional medicine for treatment of pain and inflammatory conditions …
The mucosal immune system: master regulator of bidirectional gut–brain communications
N Powell, MM Walker, NJ Talley - Nature reviews Gastroenterology & …, 2017 - nature.com
Communication between the brain and gut is not one-way, but a bidirectional highway
whereby reciprocal signals between the two organ systems are exchanged to coordinate …
whereby reciprocal signals between the two organ systems are exchanged to coordinate …
Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut
D Groeger, L O'Mahony, EF Murphy, JF Bourke… - Gut …, 2013 - Taylor & Francis
Certain therapeutic microbes, including Bifidobacteria infantis (B. infantis) 35624 exert
beneficial immunoregulatory effects by mimicking commensal-immune interactions; …
beneficial immunoregulatory effects by mimicking commensal-immune interactions; …
Tumour necrosis factor and cancer
F Balkwill - Nature reviews cancer, 2009 - nature.com
Tumour necrosis factor (TNF) is a major inflammatory cytokine that was first identified for its
ability to induce rapid haemorrhagic necrosis of experimental cancers. When efforts to …
ability to induce rapid haemorrhagic necrosis of experimental cancers. When efforts to …
Determination of half-maximal inhibitory concentration using biosensor-based protein interaction analysis
S Aykul, E Martinez-Hackert - Analytical biochemistry, 2016 - Elsevier
Half-maximal inhibitory concentration (IC 50) is the most widely used and informative
measure of a drug's efficacy. It indicates how much drug is needed to inhibit a biological …
measure of a drug's efficacy. It indicates how much drug is needed to inhibit a biological …
The role of the kinases RIP1 and RIP3 in TNF-induced necrosis
P Vandenabeele, W Declercq, F Van Herreweghe… - Science …, 2010 - science.org
Tumor necrosis factor (TNF) is a pleiotropic molecule with a crucial role in cellular stress and
inflammation during infection, tissue damage, and cancer. TNF signaling can lead to three …
inflammation during infection, tissue damage, and cancer. TNF signaling can lead to three …
Host modulation therapy with anti‐inflammatory agents
PM Preshaw - Periodontology 2000, 2018 - Wiley Online Library
Host modulation therapy refers to a treatment concept in which drug therapies are used as
an adjunct to conventional periodontal treatment to ameliorate destructive aspects of the …
an adjunct to conventional periodontal treatment to ameliorate destructive aspects of the …
[PDF][PDF] Inflammatory pathways in female reproductive health and disease
Inflammation involves alterations to vascular and immune cell function. It is well recognised
that many physiological reproductive events such as ovulation, menstruation, implantation …
that many physiological reproductive events such as ovulation, menstruation, implantation …