Current status and future perspectives on therapeutic potential of apigenin: Focus on metabolic-syndrome-dependent organ dysfunction

W Alam, C Rocca, H Khan, Y Hussain, M Aschner… - Antioxidants, 2021 - mdpi.com
Metabolic syndrome and its associated disorders such as obesity, insulin resistance,
atherosclerosis and type 2 diabetes mellitus are globally prevalent. Different molecules …

Catechin and quercetin attenuate adipose inflammation in fructose‐fed rats and 3T3‐L1 adipocytes

MA Vazquez Prieto, A Bettaieb… - Molecular nutrition & …, 2015 - Wiley Online Library
Scope This study evaluated the capacity of dietary catechin (C), quercetin (Q), and the
combination of both (CQ), to attenuate adipose inflammation triggered by high fructose (HFr) …

Natural products as modulators of sirtuins

B Karaman Mayack, W Sippl, F Ntie-Kang - Molecules, 2020 - mdpi.com
Natural products have been used for the treatment of human diseases since ancient history.
Over time, due to the lack of precise tools and techniques for the separation, purification, and …

A major intestinal catabolite of quercetin glycosides, 3-hydroxyphenylacetic acid, protects the hepatocytes from the acetaldehyde-induced cytotoxicity through the …

Y Liu, T Myojin, K Li, A Kurita, M Seto… - International journal of …, 2022 - mdpi.com
Aldehyde dehydrogenases (ALDHs) are the major enzyme superfamily for the aldehyde
metabolism. Since the ALDH polymorphism leads to the accumulation of acetaldehyde, we …

[HTML][HTML] LPS-induced renal inflammation is prevented by (−)‐epicatechin in rats

PD Prince, L Fischerman, JE Toblli, CG Fraga… - Redox biology, 2017 - Elsevier
This work investigated the capacity of (−)-epicatechin to prevent the renal damage induced
by LPS administration in rats. Male Sprague Dawley rats were fed for 4 days a diet without or …

The healthy effects of strawberry bioactive compounds on molecular pathways related to chronic diseases

F Giampieri, TY Forbes‐Hernandez… - Annals of the New …, 2017 - Wiley Online Library
It is generally accepted that a fruit and vegetable–enriched diet is favorable for human
health. The consumption of strawberries, in particular, has been related to the maintenance …

Structurally different flavonoid subclasses attenuate high-fat and high-fructose diet induced metabolic syndrome in rats

J Zhang, L Zhao, Q Cheng, B Ji, M Yang… - Journal of agricultural …, 2018 - ACS Publications
Metabolic syndrome is a serious health problem worldwide. Increasing evidence indicates
that flavonoid-rich foods exert beneficial effects. However, the function of flavonoids in …

Polyphenol levels are inversely correlated with body weight and obesity in an elderly population after 5 years of follow up (the randomised PREDIMED study)

X Guo, A Tresserra-Rimbau, R Estruch… - Nutrients, 2017 - mdpi.com
Overweight and obesity have been steadily increasing in recent years and currently
represent a serious threat to public health. Few human studies have investigated the …

Green cardamom supplementation improves serum irisin, glucose indices, and lipid profiles in overweight or obese non-alcoholic fatty liver disease patients: a double …

M Daneshi-Maskooni, SA Keshavarz… - … and alternative medicine, 2019 - Springer
Background Despite the reported health effects of cardamom on dyslipidemia,
hepatomegaly, and fasting hyperglycemia, no human research has studied its potency in …

(−)-Epicatechin and the comorbidities of obesity

E Cremonini, DE Iglesias, J Kang, GE Lombardo… - Archives of Biochemistry …, 2020 - Elsevier
Obesity has major adverse consequences on human health contributing to the development
of, among others, insulin resistance and type 2 diabetes, cardiovascular disease, non …