Nerve growth factor (NGF) was discovered in the early 1950s due to its trophic (survival-and
growth-promoting) effects on sensory and sympathetic neurons (Levi-Montalcini and …

Brain‐derived neurotrophic factor (BDNF) is a neurotrophin, which plays an important role in
the central nervous system, and systemic or peripheral inflammatory conditions, such as …

We found that a short exercise period enhanced cognitive function on the Morris water maze
(MWM), such that exercised animals were significantly better than sedentary controls at …

Experience-dependent plasticity shapes postnatal development of neural circuits, but the
mechanisms that refine dendritic arbors, remodel spines, and impair synaptic activity are …

Neurons are specialized cells with a complex morphology that represent the functional unit
of the nervous system. They are generated in remarkable numbers, particularly in higher …

Stroke remains the leading cause of long-term disability with limited options available to aid
in recovery. Significant effort has been made to try and minimize neuronal damage following …

The decline observed during aging involves multiple factors that influence several systems.
It is the case for learning and memory processes which are severely reduced with aging. It is …

Astrocyte-neuron interactions protect neurons from iron-mediated toxicity. As dopamine can
be metabolized to reactive quinones, dopaminergic neurons are susceptible to oxidative …

Brain derived neurotrophic factor (BDNF) is well recognized for its neuroprotective functions,
via activation of its high affinity receptor, tropomysin related kinase B (TrkB). In addition …

Action potential propagation links information processing in different regions of the dendritic
tree. To examine the contribution of dendritic morphology to the efficacy of propagation …