Sex and gender differences in the brain cholinergic system and in the response to therapy of Alzheimer disease with cholinesterase inhibitors

E Giacobini, G Pepeu - Current Alzheimer Research, 2018 - ingentaconnect.com
This review has two aims. First, to examine whether or not sex and gender may influence the
brain cholinergic system in animals and in humans. Second, to examine the available …

Oophorectomy, menopause, estrogen, and cognitive aging: the timing hypothesis

WA Rocca, BR Grossardt, LT Shuster - Neurodegenerative Diseases, 2010 - karger.com
Background: The concept of neuroprotective effects of estrogen in women remains
controversial. Objective: To explore the timing hypothesis in relation to cognitive aging and …

Influence of estradiol, stress, and 5-HT2A agonist treatment on brain-derived neurotrophic factor expression in female rats

I Cavus, RS Duman - Biological psychiatry, 2003 - Elsevier
BACKGROUND: Estradiol affects neuronal plasticity, mood, and cognition. We examined the
effects of the estrous cycle, acute and chronic estradiol treatments on BDNF mRNA …

Estrogen receptor螃 distribution in the human hypothalamus in relation to sex and endocrine status

FPM Kruijver, R Balesar, AM Espila… - Journal of …, 2002 - Wiley Online Library
The present study reports the first systematic rostrocaudal distribution of estrogen receptor螃
immunoreactivity (ERαir) in the human hypothalamus and its adjacent areas in young …

Estrogen and Alzheimer's disease: the story so far

B Cholerton, CE Gleason, LD Baker, S Asthana - Drugs & aging, 2002 - Springer
The ovarian hormone estrogen has long been used to treat the physical symptoms of
menopause and to aid in the prevention of osteoporosis in postmenopausal women …

The cognitive effects of ovariectomy and estrogen replacement are modulated by aging

AV Savonenko, AL Markowska - Neuroscience, 2003 - Elsevier
Recent experimental and clinical studies suggest that estrogen may be an important factor
influencing neuronal function during normal and pathological aging. Using different …

Interrelationships between hormones, behavior, and affect during adolescence: understanding hormonal, physical, and brain changes occurring in association with …

JL Cameron - Annals of the New York Academy of Sciences, 2004 - Wiley Online Library
This paper summarizes the goals of this section and considers current knowledge about the
association between hormonal changes that occur over pubertal development and the …

Estrogenreceptor螃 distribution in the human hypothalamus: Similarities and differences with ERα distribution

FPM Kruijver, R Balesar, AM Espila… - Journal of …, 2003 - Wiley Online Library
This study reports the first systematic rostrocaudal distribution of estrogen receptor beta
immunoreactivity (ERβir) in the human hypothalamus and adjacent areas in five males and …

Establishment of the concurrent experimental model of osteoporosis combined with Alzheimer's disease in rat and the dual-effects of echinacoside and acteoside from …

Y Chen, YQ Li, JY Fang, P Li, F Li - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Cistanche tubulosa is a precious traditional Chinese
medicine that has been widely used in the treatment of osteoporosis and Alzheimer's …

Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity

M Weinstock, S Shoham - Journal of Neural Transmission, 2004 - Springer
Three models are described in rats which attempt to mimic morphological and behavioural
pathology of Alzheimer's dementia; intracerebroventricular injection of streptozotocin (STZ) …