Estradiol interacts with the cholinergic system to affect verbal memory in postmenopausal women: evidence for the critical period hypothesis
J Dumas, C Hancur-Bucci, M Naylor, C Sites… - Hormones and …, 2008 - Elsevier
Estradiol has been shown to interact with the cholinergic system to affect cognition in
postmenopausal women. This study further investigated the interaction of estradiol and …
postmenopausal women. This study further investigated the interaction of estradiol and …
Male mice exhibit better spatial working and reference memory than females in a water-escape radial arm maze task
JE Gresack, KM Frick - Brain research, 2003 - Elsevier
The present study examined sex differences in spatial working and reference memory in
C57BL/6 mice. Males and females were tested in a version of the spatial 8-arm radial arm …
C57BL/6 mice. Males and females were tested in a version of the spatial 8-arm radial arm …
Understanding the cognitive impact of the contraceptive estrogen Ethinyl Estradiol: tonic and cyclic administration impairs memory, and performance correlates with …
SE Mennenga, JE Gerson, SV Koebele… - …, 2015 - Elsevier
Ethinyl Estradiol (EE), a synthetic, orally bio-available estrogen, is the most commonly
prescribed form of estrogen in oral contraceptives, and is found in at least 30 different …
prescribed form of estrogen in oral contraceptives, and is found in at least 30 different …
Alzheimer's disease, apolipoprotein E and hormone replacement therapy
H Depypere, A Vierin, S Weyers, A Sieben - Maturitas, 2016 - Elsevier
Alzheimer's disease is the most frequent cause of dementia in older patients. The
prevalence is higher in women than in men. This may be the result of both the higher life …
prevalence is higher in women than in men. This may be the result of both the higher life …
Neuroprotective activities of estrogen: an update
C Behl, D Manthey - Journal of neurocytology, 2000 - Springer
For many molecules, which have been found first in a certain tissue and with a certain
activity in the body, multiple activities have been discovered decades later. The steroidal …
activity in the body, multiple activities have been discovered decades later. The steroidal …
Targets, trials and tribulations in Alzheimer therapeutics
R Gharat, G Dixit, M Khambete, A Prabhu - European Journal of …, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
abnormal accumulation of extracellular amyloid beta senile plaques and intracellular …
abnormal accumulation of extracellular amyloid beta senile plaques and intracellular …
Hippocampal estrogen β-receptor immunoreactivity is increased in Alzheimer's disease
E Savaskan, G Olivieri, F Meier, R Ravid… - Brain research, 2001 - Elsevier
Post-menopausal estrogen use reduces the risk and severity of Alzheimer's disease (AD).
The present study investigates the distribution of both estrogen receptors ERα and ERβ in …
The present study investigates the distribution of both estrogen receptors ERα and ERβ in …
Reproductive history and risk of cognitive impairment in elderly women: a cross-sectional study in eastern China
FD Li, F He, TR Chen, YY Xiao, ST Lin… - Journal of …, 2016 - content.iospress.com
Background: Epidemiological studies suggest that proxies of higher lifetime estrogen
exposure are associated with better cognitive function in postmenopausal women, but this …
exposure are associated with better cognitive function in postmenopausal women, but this …
Subcellular relationships between cholinergic terminals and estrogen receptor螃 in the dorsal hippocampus
LA Towart, SE Alves, V Znamensky… - Journal of …, 2003 - Wiley Online Library
Cholinergic septohippocampal neurons are affected by circulating estrogens. Previously, we
found that extranuclear estrogen receptor螃 (ERα) immunoreactivity in presynaptic profiles …
found that extranuclear estrogen receptor螃 (ERα) immunoreactivity in presynaptic profiles …
Estrogen effects on cognition and hippocampal transcription in middle-aged mice
KK Aenlle, A Kumar, L Cui, TC Jackson, TC Foster - Neurobiology of aging, 2009 - Elsevier
Young and middle-aged female mice were ovariectomized and given cyclic injections of
either estradiol or vehicle treatments. During the fifth week after surgery the Morris water …
either estradiol or vehicle treatments. During the fifth week after surgery the Morris water …