A cross-sectional study of hormone treatment and hippocampal volume in postmenopausal women: evidence for a limited window of opportunity.

KI Erickson, MW Voss, RS Prakash, L Chaddock… - …, 2010 - psycnet.apa.org
The influence of hormone treatment on brain and cognition in postmenopausal women has
been a controversial topic. Contradictory patterns of results have prompted speculation that …

Estrogen and neurodegeneration

S Gandy - Neurochemical research, 2003 - Springer
Although estrogen is best known for its effects on the maturation and differentiation of the
primary and secondary sex organs, increasing evidence suggests that its influence extends …

Dissecting natural sensory plasticity: hormones and experience in a maternal context

JA Miranda, RC Liu - Hearing research, 2009 - Elsevier
There is a growing consensus that the auditory system is dynamic in its representation of
behaviorally relevant sounds. The auditory cortex in particular seems to be an important …

Effects of ovariectomy, 192 IgG-saporin-induced cortical cholinergic deafferentation, and administration of estradiol on sustained attention performance in rats.

J McGaughy, M Sarter - Behavioral neuroscience, 1999 - psycnet.apa.org
Female ovariectomized (OVX) and sham-OVX rats were trained in a task designed to assess
sustained attention. After achieving asymptotic performance, OVX rats did not exhibit the …

The role of cholinergic agents in the management of behavioural disturbances in Alzheimer's disease

JL Cummings - International Journal of …, 2000 - academic.oup.com
Alzheimer's disease (AD) is characterized by progressive cognitive deterioration,
neuropsychological or behavioural disturbances, and eventual elementary neurological …

Estrogen and NMDA receptor antagonism: effects upon reference and working memory

IA Wilson, J Puoliväli, T Heikkinen… - European journal of …, 1999 - Elsevier
Since both estrogen and NMDA receptor antagonists act on the hippocampus CA1 region
and behaviorally affect hippocampal memory tasks, we examined how estrogen depletion …

The impact of age-related ovarian hormone loss on cognitive and neural function

MI Boulware, BA Kent, KM Frick - Behavioral neurobiology of aging, 2012 - Springer
On average, women now live one-third of their lives after menopause. Because menopause
has been associated with an elevated risk of dementia, an increasing body of research has …

Young coconut juice, a potential therapeutic agent that could significantly reduce some pathologies associated with Alzheimer's disease: novel findings

N Radenahmad, F Saleh, K Sawangjaroen… - British Journal of …, 2011 - cambridge.org
Brains from ovariectomised (ovx) rats can display features similar to those observed in
menopausal women with Alzheimer's disease (AD), and oestrogen seems to play a key role …

Calcineurin as a potential contributor in estradiol regulation of hippocampal synaptic function

KM Sharrow, A Kumar, TC Foster - Neuroscience, 2002 - Elsevier
Estradiol influences Ca2+ regulation and Ca2+-dependent synaptic plasticity, suggesting
estrogenic effects on Ca2+-dependent enzymes that regulate synaptic plasticity may …

[图书][B] Alzheimer's disease decoded: The history, present, and future of Alzheimer's disease and dementia

R Sahyouni, N Brown, J Chen - 2017 - World Scientific
The human brain is the most impressive structure Mother Nature has created. In fact, it is the
most complex structure in the observable universe. It is capable of producing emotion …