Following the global declaration of indigenous wild poliovirus type 2 eradication in 2015, the
world switched to oral polio vaccine (OPV) that removed the type 2 component. This …

Background To minimize the risk of vaccine-derived poliovirus emergences, the novel oral
poliovirus vaccine type 2 (nOPV2), was bioengineered to have increased genetic stability …

Now, more than 20 years after the initial target for polio eradication, the Global Polio
Eradication Initiative (GPEI) remains off track in its mission to stop and prevent the …

Background: The safety of the COVID-19 mRNA vaccine in the outpatient setting has been
extensively studied; however, there need to be more reports that specifically assess their …

Vaccination with Sabin oral poliovirus vaccine (OPV) results in robust intestinal and humoral
immunity and has been key to controlling poliomyelitis. However, as with any RNA virus …

Polio is an infectious disease, contracted predominantly by children, that can lead to the
permanent paralysis of various body parts and can ultimately cause death by immobilizing …

The codon usage and dinucleotide frequencies of an organism depend mostly on its
nucleotide composition, but also on the evolutionary forces that have acted on its genome …

Environmental surveillance was recommended for risk mitigation in a novel oral polio
vaccine-2 (nOPV2) clinical trial (M5-ABMG) to monitor excretion, potential circulation, and …

Methods a cross-sectional assessment was conducted in Nigeria during March-June 2021
in 117 local government areas (LGAs) across 6 states and the Federal Capital Area with …

Résumé Lancé en 1988, le programme d'éradication de la poliomyélite vise à éradiquer les
poliovirus, agents étiologiques de la maladie. Coordonné par l'Organisation mondiale de la …