Bear bile has been used in Traditional Chinese Medicine for thousands of years due to its
therapeutic potential and clinical applications. The tauroursodeoxycholic acid (TUDCA), one …

Alzheimer's (or Alzheimer) disease (AD) is the most prevalent subset of dementia, affecting
elderly populations worldwide. The cumulative costs of the AD care are rapidly accelerating …

Alzheimer's disease (AD) is the most common form of dementia and one of the major causes
of disability and dependency in older people. Accumulating evidences link gut microbiota …

The prevalence of somatic insulinopathies, like metabolic syndrome (MetS), obesity, and
type 2 diabetes mellitus (T2DM), is higher in Alzheimer's disease (AD), autism spectrum …

Protein tyrosine phosphatase 1B (PTP1B) is a typical member of the PTP family, considered
a direct negative regulator of several receptor and receptor-associated tyrosine kinases …

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder with a complex
pathophysiology. Type 2 diabetes (T2D) is a strong risk factor for AD that shares similar …

Transgenic rodent models were created to decipher pathogenic mechanisms associated
with Alzheimer's disease (AD), and behavioral apparatuses such as the Morris water maze …

Alzheimer's disease (AD) is a fatal cognitive disorder with proteinaceous brain deposits,
neuroinflammation, cerebrovascular dysfunction, and extensive neuronal loss over time. AD …

Amyloid precursor protein (APP) is a transmembrane precursor protein that is widely
expressed in the central nervous system and peripheral tissues in the liver and pancreas …

Alzheimer's disease (AD) is a progressive devastating neurodegenerative disorder
characterized by extracellular amyloid beta (Aβ 42) plaque formation, hyperphosphorylation …