Long noncoding RNAs (lncRNAs) are a class of noncoding transcripts characterized with
more than 200 nucleotides of length. Unlike their names, some short open reading frames …

Cardiac fibrosis plays an indispensable role in cardiac tissue homeostasis and repair after
myocardial infarction (MI). The cardiac fibroblast-to-myofibroblast differentiation and …

Abstract microRNA-34, a highly conserved microRNA in evolution, is of great interest in
recent years. miR-34 regulates multiple targets and performed many functions in cells, such …

Long non-coding RNAs (lncRNAs) are expressed aberrantly in cardiac disease, but their
roles in cardiac hypertrophy are still unknown. Here we sought to identify a specific lncRNA …

Myofibroblasts escape apoptosis and proliferate abnormally under pathological conditions,
especially fibrosis; they synthesize and secrete a large amount of extracellular matrix (ECM) …

Myocardial infarction is the most prevalent cardiovascular disease worldwide, and it is
defined as cardiomyocyte cell death due to a lack of oxygen supply. Such a temporary …

Fibrosis is a common denominator in many pathologies and crucially affects disease
progression, drug delivery efficiency and therapy outcome. We here summarize therapeutic …

Myocardial infarction (MI) is the most prevalent cardiac disease with high mortality, leading
to severe heart injury. Circular RNAs (circRNAs) are a new type of regulatory RNAs and …

冠状动脉慢性完全闭塞病变(CTO) 已成为冠心病介入治疗中的热点之一. 寻找敏感并特异的外周
血生物标志物, 用于高危CTO 人群的早期筛查, 将有助于该疾病的预测和治疗. 近年来研究表明 …

Myocardial infarction (MI) is the most frequent end-point of cardiovascular pathology,
leading to higher mortality worldwide. Due to the particularity of the heart tissue, patients …