Bipolar depression (BD) is a highly prevalent condition with limited therapeutic options.
Deep (H1-coil) transcranial magnetic stimulation (dTMS) is a novel TMS modality with …

Abstract Treatment innovation for bipolar disorder has been hampered by a lack of
techniques to capture a hallmark symptom: ongoing mood instability. Mood swings persist …

Objective Treatment of bipolar depression is complicated by variable response and risk of
switch to mania. Guidance is informed by the strength of evidence rather than by …

BackgroundMost people with bipolar disorder spend a significant percentage of their lifetime
experiencing either subsyndromal depressive symptoms or major depressive episodes …

Optimal treatments for bipolar depression, and the relative value of specific drugs for that
purpose, remain uncertain, including agents other than antidepressants. We searched for …

Objectives The Bipolar Disorders: Improving Diagnosis, Guidance, and Education (BRIDGE‐
II‐Mix) study aimed to estimate the frequency of mixed states in patients with a major …

This paper focuses on depression that precedes an onset of manifest bipolar disorder as
early stage bipolar disorder. First, we review how to pragmatically identify the clinical …

Objective To conduct a meta‐analysis investigating the prevalence of pain in people with
bipolar disorder (BD). Method A systematic review and random effects meta‐analysis …

Objective: The authors sought to determine the risk of treatment-emergent mania associated
with methylphenidate, used in monotherapy or with a concomitant mood-stabilizing …

Objective In this paper, we aimed at reviewing evidence‐based treatment options for bipolar
mania and proposed tentative evidence‐based clinical suggestions regarding the …