Background Bipolar spectrum disorders are frequently under-recognized and/or
misdiagnosed in various settings. Several influential publications recommend the routine …

Abstract Lower Urinary Tract Symptoms (LUTS) are frequently present in the general
population as patients age with approximately a third of individuals experiencing LUTS …

Bipolar disorder is associated with high mortality, and people with this disorder on average
may die 10–20 years earlier than the general population. This excess and premature …

Background Lithium is a first line treatment option in bipolar disorder, but several alternative
treatments have been introduced in recent years, such as antiepileptic and atypical …

Introduction: In this study we estimated the rate and the trajectory of cognitive impairment in
a naturalistic sample of outpatients with major depressive disorder (MDD) and bipolar …

Objective: To perform a detailed, qualitative review of existing literature on the co-
occurrence of bipolar disorder and metabolic syndrome, the impact of metabolic …

Background Treatment‐emergent mania (TEM) represents a common phenomenon
inconsistently reported across primary studies, warranting further assessment. Methods A …

Background Comorbid anxiety in bipolar disorder (BD) is associated with greater illness
severity, reduced treatment response, and greater impairment. Treating anxiety in the …

The re-emergence (ie 'breakthrough') of depressive symptoms despite maintenance
treatment of depression with antidepressant drugs is a complex clinical phenomenon …

Mood is the changing expression of emotion and can be described as a spectrum. The
outermost ends of this spectrum highlight two states, the lowest low, melancholia, and the …