Oxidative stress, free radicals and antioxidants: Potential crosstalk in the pathophysiology of human diseases

P Chaudhary, P Janmeda, AO Docea… - Frontiers in …, 2023 - frontiersin.org
Introduction: Free radicals are reactive oxygen species that constantly circulate through the
body and occur as a side effect of many reactions that take place in the human body. Under …

Oxidative stress in cancer cell metabolism

S Arfin, NK Jha, SK Jha, KK Kesari, J Ruokolainen… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are important in regulating normal cellular processes
whereas deregulated ROS leads to the development of a diseased state in humans …

Macrophage M1/M2 polarization

C Yunna, H Mengru, W Lei, C Weidong - European journal of …, 2020 - Elsevier
Macrophages can be affected by a variety of factors to change their phenotype and thus
affect their function. Activated macrophages are usually divided into two categories, M1-like …

Role of reactive oxygen species in cancer progression: molecular mechanisms and recent advancements

V Aggarwal, HS Tuli, A Varol, F Thakral, MB Yerer… - Biomolecules, 2019 - mdpi.com
Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous
ROS production in normal cells is controlled by the appropriate regulation between the silver …

Self‐Supply of O2 and H2O2 by a Nanocatalytic Medicine to Enhance Combined Chemo/Chemodynamic Therapy

S Gao, Y Jin, K Ge, Z Li, H Liu, X Dai… - Advanced …, 2019 - Wiley Online Library
Combined chemo/chemodynamic therapy is a promising strategy to achieve an improved
anticancer effect. However, the hypoxic microenvironment and limited amount of H2O2 in …

Measurement and clinical significance of biomarkers of oxidative stress in humans

I Marrocco, F Altieri, I Peluso - Oxidative medicine and cellular …, 2017 - Wiley Online Library
Oxidative stress is the result of the imbalance between reactive oxygen species (ROS)
formation and enzymatic and nonenzymatic antioxidants. Biomarkers of oxidative stress are …

Reactive oxygen species and cancer paradox: to promote or to suppress?

S Galadari, A Rahman, S Pallichankandy… - Free Radical Biology …, 2017 - Elsevier
Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

Reactive oxygen species (ROS) and cancer: Role of antioxidative nutraceuticals

S Prasad, SC Gupta, AK Tyagi - Cancer letters, 2017 - Elsevier
Extensive research over the past half a century indicates that reactive oxygen species (ROS)
play an important role in cancer. Although low levels of ROS can be beneficial, excessive …

Recent advances in augmenting Fenton chemistry of nanoplatforms for enhanced chemodynamic therapy

SL Li, X Chu, HL Dong, HY Hou, Y Liu - Coordination Chemistry Reviews, 2023 - Elsevier
The past few years have witnessed the rise of chemodynamic therapy (CDT) as an emerging
strategy for malignant tumors suppression. Nanoplatform-based CDT has great potential …

Toxic reactive oxygen species enhanced synergistic combination therapy by self‐assembled metal‐phenolic network nanoparticles

Y Dai, Z Yang, S Cheng, Z Wang, R Zhang… - Advanced …, 2018 - Wiley Online Library
Engineering functional nanomaterials with high therapeutic efficacy and minimum side
effects has increasingly become a promising strategy for cancer treatment. Herein, a reactive …