[HTML][HTML] Possible Roles of Extracellular Vesicles in the Pathogenesis and Interventions of Immune-Mediated Central Demyelinating Diseases

C Teekaput, K Thiankhaw, N Chattipakorn… - Experimental …, 2024 - ncbi.nlm.nih.gov
Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) are two of the
most devastating immune-mediated central demyelinating disorders. NMOSD was once …

Inhibition of microRNA-448 suppresses CD4+ T cell inflammatory activation via up-regulating suppressor of cytokine signaling 5 in systemic lupus erythematosus

J Zhang, Y Guo, Y Sun, L Chang, X Wang - Biochemical and Biophysical …, 2022 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. MicroRNA-448 (miR-
448) has a pro-inflammatory effect in various inflammation-related diseases and is up …

Decreasing lncRNA PVT1 causes Treg/Th17 imbalance via NOTCH signaling in immune thrombocytopenia

L Yu, L Zhang, Z Jiang, B Yu - Hematology, 2021 - Taylor & Francis
Objectives Immune thrombocytopenia (ITP) is an autoimmune disease. T helper cell 17
(Th17) cells are increased in peripheral blood of ITP patients. NOTCH signaling is involved …

Identification of Novel Key Genes and Pathways in Multiple Sclerosis Based on Weighted Gene Coexpression Network Analysis and Long Noncoding RNA …

Y Hao, M He, Y Fu, C Zhao, S Xiong… - Oxidative Medicine and …, 2022 - Wiley Online Library
Objective. Multiple sclerosis (MS) is an autoimmune disease of the central nervous system
characterized by chronic inflammation and demyelination. This study is aimed at identifying …

[HTML][HTML] Silencing long noncoding RNA-CES1P1 suppresses glomerular endothelial cell inflammation in diabetic nephropathy

X Zhang, L Ren, J Wei, Y Ni, L Sun, X Zhao… - International …, 2022 - Elsevier
Diabetic nephropathy (DN) has become the main cause of end-stage renal disease
worldwide. Inflammation is associated with the occurrence and development of DN, and …

[HTML][HTML] Integrated analysis of differentially expressed genes and a ceRNA network to identify hub lncRNAs and potential drugs for multiple sclerosis

T Wang, S Xu, L Liu, S Li, H Zhang, X Lu… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Objective: Multiple sclerosis (MS) is an autoimmune neuroinflammatory disease of the
nervous system. However, the precise molecular mechanisms underlying MS have yet to be …

Role of M2 macrophages-derived extracellular vesicles in IL-1β-stimulated chondrocyte proliferation and inflammatory responses

W Guo, L Su, H Zhang, Z Mi - Cell and Tissue Banking, 2023 - Springer
M2 macrophages-derived extracellular vesicles (M2-EVs) serve as a tool for the delivery of
miRNAs and play an anti-inflammatory role in diseases. This study sought to explore the role …

外泌体非编码RNA 在肝纤维化中的作用及机制.

钱南南, 唐露露, 魏涛华, 杨悦… - Journal of Clinical …, 2021 - search.ebscohost.com
肝纤维化是多种慢性肝脏疾病发展为肝硬化的初始阶段, 且是一个可逆的过程.
外泌体作为能够携带包括蛋白, 脂质, 核酸等活性物质的一种细胞外囊泡亚群 …

miR-20b-5p exerts protective effects against experimental autoimmune encephalomyelitis in mice by inhibiting NLRP3 transcription and NLRP3/ASC/caspase-1 axis …

F Zhou, F Wu, X Wang, S Yu, W Tian, O Lv - Molecular & Cellular …, 2023 - Springer
Background Experimental autoimmune encephalomyelitis (EAE) is a fatal autoimmune
disease, and microRNAs (miRNAs) play vital roles in regulating immune responses …

[HTML][HTML] Antinociceptive effects of macrophage-derived extracellular vesicles by carrying microRNA-216a

X Cai, X Xi, X Li, X Zhang, X Zhang… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Cancer-induced bone pain (CIBP) represents the pain induced by bone metastases from
malignancies. The role of extracellular vesicles (Evs) has been underscored in bone …